Articles

Variation in the Influence of Climate Parameters on Dengue Fever

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Dengue haemorrhagic fever (DHF) is the highest viral infection due to its fatality in humans. Initially, dengue only occurred in the tropics and has spread to sub-tropical areas. This disease is transmitted through the bite of vector mosquitoes, Aedes aegypti, and Aedes albopictus, so the presence of these vectors is important in the spread of dengue disease. The existence of this vector is influenced by environmental conditions. Creating a suitable environment for vector mosquitoes is determined by climatic factors, especially rainfall, temperature, and humidity. Various studies have shown that these climatic factors’ influence can vary from region to region. This article discusses the variations in the influence of these climatic factors on the incidence of DHF to enrich knowledge about the epidemiology of dengue infection. This study concludes that temperature and rainfall could have a positive or negative effect on the incidence of DHF, while humidity consistently had a positive effect on the incidence of DHF. The climate factor does not stand alone and does not directly affect the process of DHF transmission. The influence appeared through the vector’s life and the virus’s multiplication in the vector’s body.

Coxsackie virus vs Dengue, clinical case: Differential diagnosis in syndemic

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In tropical regions, the simultaneous presence of multiple infectious agents complicates diagnosis and treatment. This clinical case describes a 4-year-old boy presenting with fever, malaise, and pruritic rashes on the palms and soles, initially suspected as dengue. Laboratory results showed normal platelet and hematocrit levels, excluding dengue fever. The dermatological pattern and self-limiting course were consistent with hand-foot-and-mouth disease caused by Coxsackievirus A. Differential diagnosis between Coxsackievirus and dengue is crucial in endemic settings due to overlapping symptoms such as fever and rash. Recognition of specific dermatological manifestations—particularly vesicular or pruritic lesions on acral regions—and the absence of thrombocytopenia are key diagnostic clues. The case emphasizes the importance of clinical vigilance and basic laboratory testing to distinguish between similar viral syndromes, thereby avoiding unnecessary interventions and ensuring appropriate management in pediatric populations from dengue-endemic areas.