Tag Archive for: Glycyrrhizaglabraand Poly herbal gel

The present study has been undertaken with the aim to formulate and evaluate the new polyherbal gel formulation containing 0.3 % hydroalcoholic  extract from Trigonellafoenum-graecum and Glycyrrhiza glabra for its topical anti inflammatory activity against carrageenan induced rat paw edema method .The studies were conducted on Wistar rats of either sex (150-180g).The polyherbal gel formulation was designed by using Carbopol 934, SodiumCMC, Trigonellafoenum-graecum, Glycyrrhizaglabra  extract, Ethanol, propylene glycol 400,  methyl paraben, propyl paraben, and required amount of distilled water. The skin ph (6.8-7) was maintained by drop wise addition of tri- ethanolamine. The prepared polyherbal gels were evaluated for physical appearance, pH, spreadability, skin irritation to observe side effect. It was inferred from the results that polyherbal gel formulations were good in appearance and homogeneity. The overall result of this research the prepared poly herbal gel formulation shows significant anti-inflammatory activity.