A brief review on Triazole and its Pharmacological Application

The triazole core is one of the most imperative and well known heterocycles which is composed of nitrogen atom which forms natural products with medicinal claims. Triazole moiety is present as a principal structural component in the drug categories such as antimicrobial, anti-inflammatory, analgesic, antineoplastic, antimalarial, antiviral, antihypertensive, local anaesthetic, antianxiety, anti-Parkinson′s, antidepressant, antioxidant, antihistaminic, antitubercular, antidiabetic etc. The broad and potent activity of triazole and their derivatives has established them as pharmacologically significant platforms. The elementary heterocyclic rings present in the numerous medicinal mediators are 1,2,3-triazole and 1,2,4-triazole. A huge capacity of investigations has been approved on triazole and their results, which has proved the pharmacological status of this heterocyclic core. The current paper is an try to review the pharmacological activities reported for triazole derivatives in the current literature with an apprise of current research discoveries on this nuclei.