Magnitude and Patterns of Post-Traumatic Epilepsy among Epilepsy Patients on Follow-Up at Tikur Anbessa Specialized Hospital and Zewiditu Memorial Hospital, Addis Ababa, Ethiopia: A Cross-Sectional Study
Background: Post-traumatic epilepsy is characterized by development of at least one seizure after the first week following a traumatic brain injury (TBI). In Ethiopia, there is a lack of data regarding the prevalence of post-traumatic epilepsy among epileptic patients.
Objective: This study aimed to assess the prevalence of post-traumatic epilepsy among epilepsy patients on follow-up at Tikur Anbessa Specialized Hospital (TASH) and Zewidtu Memorial Hospital (ZMH).
Methods and materials: An institution-based cross-sectional study design was implemented among patients with epilepsy attending the neurology clinic of TASH and ZMH. Data was collected from patients and medical records using a structured questionnaire and data abstraction format respectively. Descriptive analysis was conducted to summarize the socio-demographic and clinical characteristics of participants.
Results: In this study, 280 patients with epilepsy participated from Tikur Anbesa Specialized Hospital and Zewidtu Memorial Hospital with a response rate of 85%. Among participants, 21 (7.5%) were diagnosed with post-traumatic epilepsy. The mean age of these patients was 41.5 years, with a male-to-female ratio of 1.6:1. Road traffic accidents were the primary cause of brain trauma (61.9%) and subdural hematoma (19.04%) and intraparenchymal hemorrhage (19.04%) were the commonest imaging finding. In the majority of cases (91.5%), seizures began within a period of three years following a traumatic event. Generalized tonic-clonic seizures (57.1%) were the most common seizure type and generalized epileptiform discharges (35%) were the most common EEG finding.
Conclusions: Post-traumatic epilepsy contributes significantly to the number of patients with epilepsy presenting to our neurology services, predominantly affecting the young active population, with road traffic accidents being the common mechanism.
