Perspectives of the HACCP System in the Alembic Cachaça Certification

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Cachaça is the name of a Brazilian beverage produced by distillation of fermented sugarcane juice. It is called “alembic cachaça ”  when produced in an agricultural environment, through fermentation of fresh sugarcane juice and distillation by batches in copper stills.  Due to the peculiarities of the process and the dedication of hundreds of producers, this drink achieved improved and highly differentiated sensory quality; conquering new markets and winning important prizes in national and international competitions. In this context, there is a growing search both for resources to prevent fraud in marketing and for certificates that attest to the safety of consumers’ health, especially HACCP. In this review article, we highlight the points already achieved in the standardization of the production process and introduce others that still require appropriate standardization, related to the control of pesticides in the sugarcane field, the safety of the wood used in the storage barrels and the certification of the production process. It is also proposed to review the limit of Brazilian legislation for the ethyl carbamate content.

Analysis of Social and Behavioral Impacts of Covid-19 Pandemic in Community-dwelling Older Adults Screened for Insomnia

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Objectives: This study sought to understand the impacts of the COVID-19 pandemic on older adults screened for the Nursing Diagnosis Insomnia (00095).

Methods: Secondary cross-sectional data analysis from a parent study on insomnia in older adults, using Bardin (2011) content analysis. Data from 77 older adults were collected from qualitative February to May 2021 in the pandemic period.

Results: Four thematic categories emerged: (1) Physical exercises; (2) Social impacts; (3) Physical and mental health; (4) Finances. The Physical and mental health category was most representative both in negative perceptions and in positive or neutral perceptions about the pandemic. The excess of bad news generates a negative perception. On the other hand, some older adults enjoyed benefits, such as improved sleep.

Discussion: The verbalized feelings are interconnected, and these spheres of life complement each other, interfering with each other. It is suggested to produce nursing strategies for older people and studies that address nursing interventions in pandemic periods.

The Influence of Work Competence and Work Motivation on Employee Performance at PT Hardware Clothing Area Banjarbaru

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The aim of this research is to determine: (1) The influence of work competency and work motivation simultaneously on employee performance. (2) The partial influence of work competency and work motivation on employee performance. (3) Which variable is the most dominant between work competence and work motivation on the performance of PT Hardware Clothing Area Banjarbaru employees. This research is quantitative research with a correlation design. Sampling was carried out using a saturated sampling technique with 30 respondents. The data collection technique uses a questionnaire method, then the results of the questionnaire are tested on instruments to test their validity and reliability in order to obtain results that are in accordance with the facts. Next, the data analysis technique is carried out using classical assumption tests, namely the normality test, heteroscedasticity test, and multicollinearity test as regression test requirements for hypothesis testing. The hypothesis test used is multiple linear regression analysis. The results of this research show that work competency and work motivation simultaneously influence employee performance. Partially, work competency has a significant positive effect on employee performance, while work motivation partially has no significant effect on employee performance. Work competency has the most dominant influence on employee performance.

Nutrient Content of Pig Feed Based Local Feed Mixed with Liquid Fermentation Products from Moringa and Azadirachta indica Leaf Extracts

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This research aims to determine the nutritional content of rations based on local feed mixed with liquid Moringa leaf extract and fermented Azadirachta indica as pig feed. The research materials used were Moringa leaves and Azadirachta indica which were extracted and liquid fermented as well as local rations. In this study, an experimental method was used with a completely randomized design consisting of 5 treatments and 4 replications. The treatment in this study was R0; ration without liquid fermented extract, R1; ration + 10% liquid fermented extract, R2; ration + 20% liquid fermented extract, R3; ration + 30% liquid fermented extract, R4; ration + 40% liquid fermented extract. The data obtained were analyzed using analysis of variance. Based on the research results, the crude protein content (%) R0; 13.90±0.40, R1; 15.02±0.12, R2; 17.73±0.88, R3; 19.20±0.29, R4; 20.22±0.41, crude fiber content (%) R0; 7.10±0.18, R1; 6.90±0.27, R2; 6.85±0.39, R3; 7.08± 0.17, R4; 7.04±0.14, non nitrogen free extract content (%) R0; 48.69±1.88, R1; 49.42±0.48, R2; 47.54±0.79, R3; 46.14±0 .79, R4; 45.34±0.72, gross energy content (kcal), R0; 3524±45.55, R1; 3620±26.77, R2; 3698±19.24, R3; 3742±10.88, R4; 3770±31, 28. The results of statistical analysis showed that the treatment had a significant effect of P<0.05 on crude protein, non nitrogen free extract, energy content, but had no significant effect of P>0.05 on crude fiber content. The conclusion of this research is that the addition of fermented Moringa leaf extract and Azadirachta indica liquid to local pig rations has an effect on increasing protein and energy content with an average increase in protein content of 3.36% and energy of 107.73 kcal. for each increase, add 250 ml of liquid Moringa leaf extract and fermented Azadirachta indica to the local ration.

Ameliorative Role of Grape Seed Extract (Vitis Vinifera) on Gemcitabine- Induced Testicular Damage in Rabbits

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Spermatogenesis is a highly conserved and regulated process and it is sensitive to fluctuations in the physical and chemical environment. Gemcitabine is a novel antimetabolic anticancer drug used frequently in the treatment of many cancers. Gemcitabine may disrupt spermatogenesis by targeting various testicular cell types. Grape seed extract is a natural product, recently identified as one of the most powerful antioxidants. In addition, it has been reported to exert anticarcinogenic effects.

This current work aimed to study the effect of gemcitabine on the testicular tissue of local adult rabbits and to evaluate the possible protective role of Grape seed extract.

A experimental study was performed on twenty seven  adult male local rabbits, were divided into three  groups,  nine rabbit in each group as following: group (A): animals of control group received normal saline injection,  group (B): animals of treated group received therapeutic dose of gemcitabine alone in a dose of 25 mg/kg body weight intraperitoneally once per week for six successive weeks and group (C): served as protective group and was concomitantly treated with grape seeds extract by oral gavages in a dose of 250 mg/kg body weight  and gemcitabine in a dose of 25 mg/kg body weight intraperitoneally once per week for six successive weeks.

The results of the present investigation showed that gemcitabine toxicity produced significant structural changes in the testis of group B, gemcitabine treated group, in the form of multiple distortion of the seminiferous tubules, with cellular disorganization, testicular tubular cell degeneration, necrosis, tubular atrophy, desquamation and sloughing of the seminiferous epithelium which was accumulated in the centre of the seminiferous tubules in the form of degenerated tissue.  Many seminiferous tubules showed widely spaced spermatogenic cells. Karyopyknosis, disappearance of interstitial cells of Leydig and necrotic Sertoli cells, progressive tubular and interstitial testicular damage together with spermatogenic arrest was an initial necrotic change induced by gemcitabine exposure. Disorganization of spermatogenic cells, an interruption in spermatogenesis process and the seminiferous tubules are devoid of sperms was also showed in this study.

Sections from the testes of animals received therapeutic dose of gemcitabine and treated by grape seed extract, group (C) were showing partial preservation of the normal structure of the seminiferous tubules. Most of them more or less resembled the normal structure.

It could be concluded that gemcitabine caused marked alterations in the structure of the seminiferous tubules of the rabbit testis that may be minimized by administration of grape seed extract. Our findings simply revealed that grape seeds extract treatment significantly inhibits testicular cell apoptosis, which suggests that apoptosis may be one of the underlying mechanisms by which grape seeds extract protects against gemcitabine induced defective spermatogenesis.

Discovery Learning: Learning Modules to Improve the Critical Thinking Skills of Grade IV Elementary School Students

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This research aims to develop discovery-based learning modules on Natural Sciences and Social Sciences (IPAS) subjects in elementary schools. Research and development uses the Brog and Gall (2003) model which consists of 3 main steps of research and development. In product development, researchers use the ADDIE development model to develop prototypes of learning modules. This research was conducted in the central part of Lampung Province, precisely at SD Negeri 5 Lempuyangan Regency, Bandar Way Pengubuan. The sampling technique uses random sampling by assigning 2 classes as subjets, namely the experimental class and the control class consisting of 25 students in each class. The results of this study showed that the average score of the experimental class was 77.83 and the control class was 69.43. Based on the results of the analysis, it was found that the experimental class was superior to the control class and had a significance value obtained through the t-test before 0.000, which means that there is a significant average difference. The results are then continued on the effect size test to see the magnitude of the influence of the product used. The effect size test result is 0.83 with a very high interpretation. Based on the results of research conducted in class IV, it can be concluded that discovery-based learning modules are effective in improving students’ critical thinking skills.

Work-Family Conflict among Police Personnel’s Job Satisfaction in Special Region of Yogyakarta with Gender as a Moderating Variable (Study in Police Administrative Unit at the County Level)

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Research has shown that both men and women experience work-family conflict, but the nature of the conflict differs based on gender. Women often face conflicting demands between their work and family roles, which can lead to role overload and stress. Men, on the other hand, may experience conflict when their work responsibilities interfere with their family responsibilities, but they may also experience pressure to prioritize work over family due to traditional gender norms and expectations. It is important to recognize and address these gender differences in work-family conflict in order to promote greater work-life balance and job satisfaction for all individuals.

This study aims to examine and analyze the effect of work-family conflict among police personnel’s job satisfaction in Special Region of Yogyakarta, especially at police administrative unit at county level. Moreover, this study focuses on exploring the moderating effect of gender on relationship of work-family conflict with job satisfaction. This quantitative study designed to test the hypothesis. The data for the present study were primary cross-sectional data collected from total of 193 police personnel in Yogyakarta. The result of the study show that work family-conflict have a significant negative effect on job satisfaction. Moreover, gender has no impact significantly on the relationship between work-family conflict with job satisfaction.

The Rite of Passage of Pregnancy: Illustration of the Learning Process of Islamic Religious Education Strengthening Multiculturalism

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The purpose of this paper is to describe, analyze, and interpret Islamic religious education learning practices that strengthen multiculturalism. This is done by looking at the rite of passage of pregnancy at Bangunjiwo DIY.  Finally, this paper produced several answers. The practice of Islamic religious education learning that strengthens multiculturalism in the rite of passage of pregnancy, is held in two types of rites, namely great rites and little rites. The learning of Islamic religious education in the great rite takes place at the mitoni event. While in small rites occur at ngapati events. The learning practice is held intensively and gradually, starting from preparation, implementation, and closing. Its implementation involves various elements of society, including rite organizer, religious leaders, government figures, and community members regardless of background.

The Effect of Trust, Knowledge Sharing, on Employee Performance through Organizational Commitment as an Intervening Variable in Shipping Companies in Surabaya

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Organizations strive to achieve success because the business environment is very competitive. Regardless of the size of the company and the company’s market share, every organization strives to manage employees so that they are able to work well. The company will manage its employees so that they run in line with the company’s goals, because one of the things that must be paid attention to in the company is the performance of its employees. Good employee performance can be seen from quality work results, producing quantities according to company standards, being on time, having high attendance, and being able to work together with fellow employees (Mathis and Jackson, in Damayanti et al., 2018). According to Mahmudi (2015:21), employee performance can be influenced by various factors, one of which is personal factors such as commitment. Based on Zehir et al. (2012), organizational commitment is a driver of organizational success, having the desire to fight for the organization, and belief in the goals and values ​​of the organization. Organizational commitment is a variable that is influenced by several factors. One factor that can influence organizational commitment is trust (Redha et al., 2022). Aziz and Abadiyah (2022) confirmed that there is a real influence of organizational commitment on employee performance, whereas Kertabudi and Aripin (2014) proved that there is no influence of organizational commitment on employee performance. Mukri et al. (2017), Hardiani and Prasetya (2018) prove the influence of trust on employee performance, however, research by Prasetyo et al. (2018) proves the opposite, namely that trust has no effect on employee performance. Meanwhile, trust has been proven to have no effect on employee performance with organizational commitment as an intervening variable by Aziz and Abadiyah (2022). Referring to the background described previously, it can be seen that there are still inconsistent research results regarding the influence of Trust, Knowledge Sharing, on Employee Performance through Organizational Commitment as an Intervening Variable.

Study to Assess the Prevalence of Risk Factor of Chronic Kidney Disease among Diabetes Mellitus and Hypertensive Client at Karambakkam

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Aim: The present study aims to assess the prevalence of risk factor of chronic kidney disease among diabetes mellitus and hypertensive client at karambakkam.

Methods and Materials: A Non-experimental descriptive research design was used for the present study. A total 200 samples were collected using purposive sampling technique. The demographic of diabetes mellitus and level of knowledge of risk factor of chronic kidney diseases was assessed using structured questioner and, followed by that data was gathered and analyzed.

Results: The results the study revealed that there is a significant association with the level of knowledge on risk factor of chronic kidney diseases among diabetes mellitus and hypertensive client at p<0.001.

Conclusion: Thus, the present study concluded that majority of the clients with diabetes mellitus and hypertension had inadequate knowledge and it is recommended that they should be educated on the risk factors of CKD.