A Review on the Prevalence and Management of Colorectal Cancer

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Cancer had become a common disease worldwide and cancer related death is also increasing in various parts of the world in spite of increased screening and diagnostic facilities available for early detection of cancer and availability of advanced care system. Changes in the diet and life style had led to alteration in the microenvironment of the cells leading to genetic changes and mutation. In this review, Colorectal cancer prevalence, risk factors for the development of colorectal cancer, pathogenesis, diagnosis and various treatment modalities available are discussed here.

Adulticidal Activities and Synergistic Effects of Citrus Aurantiifolia Peels and Hyptis spicigera Leaves Essential Oils against Anopheles gambiae s.l. (Diptera: Culicidae)

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Research on new plant-based insecticides meets the need for an alternative to address mosquito resistance to synthetic insecticides. This study assessed the adulticidal activity and synergistic effects of essential oils (EOs) from Citrus aurantiifolia peels and Hyptis spicigera leaves on female adults of Anopheles gambiae s.l. The extraction yields were on the order of 0.17 and 0.11%, respectively, for C. aurantiifolia and H. Spicigera EOs obtained by hydrodistillation. The phytochemical composition of the EOs was analysed by Gas Chromatography coupled with Mass Spectrometry (GC-MS).  GC-MS revealed that the essential oils of C. aurantiifolia and H. spicigera contained high amounts of monoterpene compounds (100% and 77.45%, respectively). Adulticidal activity was assessed using WHO and CDC bottle bioassays at concentrations of 2.5, 5, 7.5 and 10 mg/ml/btl. The EOs of both plants caused significant concentration-dependent Knock down and adulticidal activities. Individually, H. spicigera EOs had more adulticidal effects (LC50 = 4.42 mg/ml/btl) than did C. aurantiifolia EOs (LC50 = 6.79 mg/ml/btl). An EO mixture 25%Ca + 75%Hs from C. aurantiifolia and H. spicigera had synergistic effects (CI = 142.84; SF = 1.42) on female Anopheles gambiae adults. Combinations of the two plant EOs considerably optimize their insecticidal effectiveness.

Development of Sustainable Business Models through Internal Partnerships Efforts to Expand Consumer Reach

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This research was carried out with the aim of developing a sustainable business model through partnerships in an effort to expand consumer reach in the Makassar Modem Warehouse business. This research is a type of development research (R&D) that adapts the 4D development procedure which consists of four stages which include define(definition), design(planning), develop(development), as well disseminate (deployment). Data collection activities were carried out by means of observation, interviews and documentation. The data analysis technique uses qualitative descriptive analysis techniques. The research carried out resulted in recommendations for forms of partnership with environmental, social and economic parties that Gudang Modem Makassar can implement to increase the potential to expand consumer reach.

Using Mathematical Thinking in Solving Trigonometric Problems within Mason’s Cognitive Framework

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The paper focuses on the synergy between mathematical thinking and solving trigonometric problems within Mason’s cognitive framework. It presents and analyzes concepts related to mathematical thinking, especially Mason’s definition of the thinking process into three stages: input, impact, and evaluation. Applying this framework to solving trigonometric equations, the paper illustrates how mathematical thinking can help approach problems in an organized and rigorous manner, while opening opportunities for creativity and exploration.

Discussing mathematical thinking, the paper defines it as a creative process involving prediction, induction, interpretation, description, abstraction, and reasoning. Aligned with Mason’s definition of mathematical thinking, the paper describes how this thinking aids students in understanding complex structures and solving problems quickly and flexibly.

Exploring Pragmatics: Uncovering the Layers of Language and Meaning

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The dynamic interaction of pragmatics, semantics, and culture in language understanding and communication is examined in this narrative review. The review emphasizes how pragmatics and semantics provide complementary viewpoints on language meaning, drawing on current findings in linguistics and communication studies. Semantics concentrates on the exact meanings of words, but pragmatics takes speaker intent and context into account. Comprehending both improves meaning interpretation and communication. The research also highlights how culture influences, how language is used and understood, especially when it comes to nonverbal cues like humor and manners. Language is used to communicate and understand emotions, and this is influenced by cultural quirks. The results highlight how crucial it is to take cultural background, emotional expression, and context into account when developing language instruction and communication approaches. The study ends with recommendations for future research, such as cross-cultural comparison studies, language change monitoring longitudinal studies, and examinations of how language usage is affected by digital platforms. This review advances pragmatics knowledge, which leads to more successful communication techniques in a variety of settings.

Development of Interactive Video Learning Media Based on Articulate Storyline to Improve Students Critical Thinking Skills in Thematic Learning Grade V Elementary School

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The purpose of this study is to find out and analyze the needs of teachers and students in developing interactive video learning media based on articulate storyline to improve students’ critical thinking skills in decent grade V elementary school thematic learning. Data collection was obtained through interviews with grade V teachers and field observations. Researchers obtained information based on observations made that the critical thinking skills of grade V students of SDN 3 Bumi Nabung Timur with a percentage of 58.88%. Based on observations made by researchers, obstacles were found in the implementation of teaching and learning, namely the lack of use of learning media that supports learning. The conclusion of the learning media research has met the criteria of being very feasible. used in research. The product has met practical criteria taken from the results of educator and student response questionnaires. The practicality of the product can be seen from the activities of students in using interactive video media based on articulate storyline. The effectiveness of the product taken from comparing the improvement of students’ critical thinking skills in both samples, namely the experimental class and the control class. Based on the results of the recapitulation, it is proven that the experimental class gets an effect size value of 1.50 in the large category.

The Influence of Sustainability Disclosure on Financial Performance: A Study of Indonesian Firms

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This study examines the correlation between the disclosure of sustainability measures and the financial success of companies in Indonesia. The increasing importance of sustainability disclosure, which includes environmental, social, and governance factors, for firms to demonstrate their dedication to sustainable practices, has generated significant debate on its influence on financial results. This study investigates the impact of sustainability disclosures on the financial performance of companies in Indonesia, thus adding to the existing body of knowledge on this topic. The study utilizes a mixed-method approach, incorporating qualitative content analysis of data extracted from annual reports, as well as quantitative analysis derived from financial statements of publicly traded corporations. The sample consists of companies from three major industry sectors, each demonstrating different levels of quality in disclosing their sustainability practices. Accounting-based indicators like return on assets (ROA) and return on equity (ROE) are used to evaluate financial performance. The findings demonstrate a direct and favorable relationship between the caliber of sustainability disclosures and financial performance, specifically in sectors that are highly responsive to environmental concerns. Companies that have more comprehensive and transparent sustainability reporting processes in these industries generally achieve better performance compared to those with less comprehensive reporting. These conclusions have substantial ramifications for firms, investors, and policymakers. Enhancing sustainability disclosure can enhance a company’s financial performance and act as a significant factor for investment choices, providing information about a company’s dedication to sustainability and related risks. Policymakers can utilize these observations to support the implementation of improved sustainability reporting regulations, thereby fostering sustainable economic growth in Indonesia. Ultimately, the research confirms that Indonesian companies who provide detailed and reliable information on their sustainability efforts have a positive correlation with their financial performance. This emphasizes the significance of improving these practices to achieve both economic prosperity and sustainable development objectives.

Managing Classroom Using Real-life Experience: The concept of Freedom in Learning Implementation

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Teaching-learning activities involve various elements, such as classroom management. Learning approach is a way for teachers to manage the class because it assists them in learning activity. This study was qualitative study using data obtained from documentation and observation. Score average and percentage were employed as research technique to determine the correlation between learning approach in classroom management and learning success. This study aims to find out how real-life experience can be used as learning approach in managing art class. Accordingly, the results indicated that implementing a real-life experience-based approach in managing art classes showed a positive but insignificant effect. It seen from good category (an average of 3.00-3.75) and midterm scores that show 52.9% scored higher than 65 (passing mark), while 47.1% scored less than 65. It indicates although the approach had positive influence, it was not significant in improving students’ results.

The Correlation between the Awareness of the Dangers in Smartphone Radiation and Sleep Quality among High School Students in Thailand

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Despite smartphones’ critical benefits in several aspects of living in this generation, their emissions of radiation exert profound effects on the physical health of the affected individuals, including heightened risks of cancer as well as increased fibroblast activity of the skin. The aim of this study endeavors to determine the correlation between awareness of the dangers in utilizing smartphones before bed and sleep quality among high school students, to raise consciousness of the perils of smartphone radiation, and to observe sleep qualities among high school students. Through previous research, it was hypothesized that awareness of the dangers in smartphone radiation would negatively impact the sleep quality of the participants due to the negative ramifications of the radiation. To verify whether this also implies an impact on the Thai population, data were collected using a cross-sectional method with random samples of both Thai and international high school students. The information was later analyzed via Statistical Product and Service Solutions (SPSS). The results indicate a robust correlation between dangers in smartphone’s radiation and sleep quality (p = 0.451**), grade and sleep quality (p = 0.003*), and age and sleep quality (p = 0.002*). Moreover, a strong correlation between grade and sleep quality, as well as age and sleep quality, can be inferred that grade and age correlate with the amount of stress within individuals, having a negative effect on individuals’ sleep quality. Ultimately, this research not only analyzes the correlation in the findings but also aims to raise awareness of potential hazards in smartphone radiation among high school students to enhance their sleep quality.

Philosophical Scepticism and Western Medieval Theology. Roger Bacon: “The First True Scientist”

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The main aim of this paper is to provide evidence for the inclusion of ancient philosophical scepticism in Christian theological discourse. The context is the environment of 13th-century Western Christianity, more specifically, one of its leading representatives, the theologian Roger Bacon. The study will be structured in three main parts, except for the introductory argument and conclusions. The first part will contain biographical and ideological notes on this author, the second will record the elements of scepticism likely to be taken up by Bacon’s vision, and the last part will show the specific presence of these elements in Western theologian thinking.