Articles

Effect of Turmeric Herbal on Polycystic Ovary Syndrome: A Systematic Review

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Polycystic Ovary Syndrome (PCOS) is an endocrine disorder that is increasingly affecting women in the reproductive age group. Women commonly experience menstrual irregularities, hirsutism, weight gain, and acne, as well as the development of a complex endocrine disorder that presents with oligomenorrhea, hyperandrogenism, and polycystic ovaries. Herbal medicine is a complex intervention with the potential for synergistic and antagonistic interactions between compounds. These drugs are essential for the treatment of PCOS and have fewer side effects compared to allopathic drugs. One of the herbal medicines to treat PCOS is turmeric or curcumin, curcumin has various biological activities including antioxidant, anti-inflammatory, anti-microbial, anti-tumor, cardioprotective and neuroprotective effects involving various mechanisms. Curcumin can stimulate insulin-mediated glucose uptake via the phosphatidylinositol 3-kinsase (PI3K)/Akt pathway, which, in turn, upregulates glucose transporter 4 (GLUT4) in adipocytes and skeletal muscle, leading to increased glucose levels. Curcumin supplementation improves glycemic control and lipid metabolism, and reduces oxygen radical species in PCOS patients. Curcumin is a diarylheptanoid derived from the rhizome of the Curcuma longa plant, which functions as an anti-inflammatory and antioxidant which is very important in the treatment of PCOS. In addition, nearly half of patients with PCOS develop metabolic syndrome and insulin resistance, and are associated with a much higher risk of type 2 diabetes mellitus.

Analysis of Role of Turmeric in Management of Alveolar Osteitis

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Background and objective: Alveolar osteitis created disruption in healing process after clot foration but before wound organization. The main objective of the study is to analyse the role of turmeric in management of alveolar osteitis.

Material and methods: This descriptive cross sectional study was conducted in DHQ Sargodha during Nov 2019 to Jan 2020. This study was done with the permission of ethical committee of hospital. There were 180 participants in this study. Data was collected from two study groups, one was treated with turmeric and group B was treated with Zinc oxide eugenol (Alveogel).

Results: The data was collected from 180 patients, 90 patients in each group. Group A shows symtopms of pain, swelling and halitosis from second day while Group B shows all these symptoms around day 5th. According to t-test there was a significant difference between two treatments. The significant value of p < 0.05. There was no side effect of turmeric observed in our study, so it can be used as an alternative for the management of dry socket.

Conclusion: It is concluded that there are no side-effects of turmeric. Excess use of euginol, can lead to necrosis of bone. The turmeric can be used as a medicament for the management of dry socket. Excess use of eugenol can lead to necrosis of bone.