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Biopsychosocial Model Analysis of Risk Factors for Suicide in Mexico: Systematic Review (2019–2024)

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 Suicidal behavior in Mexico constitutes an urgent public health problem, that requires integrating biological, psychological, and social dimensions. The objective of this systematic review was to identify and organize risk factors associated with death by suicide in Mexican population between 2019 and 2024, using the biopsychosocial model as a theoretical framework. The protocol was registered in PROSPERO (CRD420251131626) and followed the PRISMA 2020 guidelines. A structured search was conducted in PubMed, inclusion and exclusion criteria were applied; three independent authors performed a quality analysis; 110 full-text articles were evaluated, and 57 were included for the final analysis.

The findings were organized into 75 categories grouped by biopsychosocial domains. Psychological factors were the most frequent, highlighting depression, anxiety, emotional dysregulation, hopelessness, impulsivity, and self-harming behaviors. At the biological level, studies identified associations with sex, age, chronic diseases, substance use, and emerging findings in genetics, neuroendocrinology, and physiological markers. In the social dimension, interpersonal violence, adverse experiences in childhood, low social and family support, socioeconomic inequalities, and stigma predominated. Persistent methodological limitations were also observed in the studies reviewed, including the predominance of cross-sectional designs, convenience samples, heterogeneous instruments, and limited representation of structurally vulnerable populations.

The results show that Mexican research remains fragmented, focusing mainly on individual factors and providing little integrative analysis across biological, psychological, and social dimensions. So, it is required to evolve towards robust explanatory models incorporating longitudinal methodologies, a gender perspective, intersectional approaches, and multivariate frameworks that allow the understanding of individual vulnerability and structural conditions.

Analysis of Risk Factors and Mapping of Helminth Infection Incidence in the Working Area of Nulle Public Health Center, South Central Timor Regency

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Background: Soil-Transmitted Helminth (STH) infections remain a public health concern in tropical regions, particularly among school-aged children, while local data and risk mapping in the service area of Nulle Primary Health Center are limited.

Objective: To estimate the prevalence of STH infection, identify water, sanitation, and hygiene (WASH)–related risk factors, and spatially map infection clusters among primary schoolchildren in South Central Timor, Indonesia.

Methods: A cross-sectional survey was conducted in seven primary schools from 10–16 June 2025, involving 263 students. Data on WASH-related behaviors and environmental conditions were collected using structured questionnaires. Stool samples were examined using the direct smear method with 2% eosin and 2% lugol’s iodine. Bivariate analysis was performed using Fisher’s exact test with α = 0.05. Geographic household coordinates of STH-positive cases were mapped using ArcGIS to identify spatial clusters.

Results: The prevalence of helminth infection was 4.6% (12/263). The most common species identified was Ascaris lumbricoides (83.3%), followed by Trichuris trichiura and mixed infections (each 8.3%). Handwashing habits, nail trimming, consumption of raw food, use of footwear, latrine ownership, and household water source were significantly associated with infection (p<0.05). GIS mapping revealed high-risk areas in Nulle, Tublopo, and Benlutu villages, characterized by high soil humidity, suitable temperature and soil type, as well as poor sanitation conditions.

Conclusion: STH infection in the Nulle area remains a concern, influenced by hygiene behaviors and environmental conditions. Location-based promotive and preventive efforts are essential to reduce infection rates.

The Effect of Knee Injury and Sedentary Behavior on the Incidence of Knee Osteoarthritis at Muhammadiyah Metro General Hospital

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Knee osteoarthritis is one of the most common degenerative joint diseases found in adults and the elderly. This disease causes pain, stiffness, limited movement, and impacts the quality of life of sufferers. The risk factors for osteoarthritis are multifactorial, but among the modifiable factors, a history of knee injury and sedentary behavior are of particular concern because they have been shown to contribute to the onset of osteoarthritis. This study aims to determine the relationship between a history of knee injury and sedentary behavior with the incidence of knee osteoarthritis at Muhammadiyah Metro General Hospital. The study design is an observational analysis with a case-control approach. The sample consisted of 152 respondents, comprising 76 cases (patients with knee osteoarthritis) and 76 controls (patients without knee osteoarthritis). Data were collected through interviews using structured questionnaires and medical record reviews. Bivariate analysis was performed using the Chi-square test with odds ratio (OR) calculations and 95% confidence intervals. A total of 38.2% of respondents had a history of knee injury and 12.5% had sedentary behavior. The test results showed a significant relationship between a history of knee injury and the incidence of knee osteoarthritis (p = 0.000; OR = 6.089; 95% CI: 2.913–12.729). In addition, sedentary behavior was also significantly associated with the occurrence of knee osteoarthritis (p = 0.000; OR = 23.276; 95% CI: 3.019–179.476). This study shows that a history of knee injury and sedentary behavior are significant risk factors for the occurrence of knee osteoarthritis in patients at Muhammadiyah Metro General Hospital.

Obesity and Cholinesterase Level Related to Impaired Fasting Glucose in Indonesian Farmers

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Obesity is characterized by the excessive accumulation of fat caused by mutations in the leptin gene and its receptors. In Indonesia, the incidence of childhood obesity increased from 6.4% in 2007 to 9.2% in 2010. The prevalence and risk factors for childhood obesity in rural Indonesia, particularly in Teluk Pandan Subdistrict, Pesawaran District, Lampung Province, have not been extensively studied. This study aims to determine the prevalence and risk factors for childhood obesity in this rural-coastal area. A survey method was used for the prevalence study, and a case-control approach was used to identify risk factors. The study involved 94 students from elementary schools in Teluk Pandan, matched based on obesity status, gender, and age. Obesity was defined as a BMI at or above the 95th percentile of the CDC chart. Variables measured included dietary patterns, lack of physical activity, family income, parental obesity status, early introduction of complementary foods, and history of exclusive breastfeeding, analyzed using chi-square tests. The results showed that 148 out of 3190 children were overweight. Identified risk factors included excessive food consumption (p=0.0001; OR=15.622; CI95% 5.702-42.803), lack of physical activity (p=0.0001; OR=7.714; CI95% 2.868-20.751), high family income (p=0.0096; OR=2.202; CI95% 0.958-5.059), parental obesity status (p=0.0001; OR=24.5; CI95% 7.870-76.271), early introduction of complementary foods (p=0.0001; OR=4.567; CI95% 1.916-10.888), and non-exclusive breastfeeding (p=0.0005; OR=4.046; CI95% 1.605-10.201). The prevalence of childhood obesity in Teluk Pandan is 46% lower compared to urban areas in Indonesia. This study identifies several risk factors associated with childhood obesity in rural-coastal areas, including excessive food consumption, lack of physical activity, parental obesity, early introduction of complementary foods, and non-exclusive breastfeeding.

The Study to Assess the Prevalence of Iron Deficiency Anemia and Associated Risk Factors among Women

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Aim: The present study aims to assess the Prevalence of Iron Deficiency Anemia and Associated Risk factors among women at SMCH.

Methods and Materials: A descriptive research design was used for the present study. A total 50 samples were collected using quota sampling technique. The demographic variable and level of prevalence of iron deficiency was assessed using structured questioner and, followed by that data was gathered and analyzed.

Results: The results the study revealed that there is a significant association with level of prevalence of iron anemia and associate risk factors among women at p<0.05.

Conclusion: Thus, the present study assessed the prevalence of iron anemia and associate risk factors among women and it was evident there is a lack of awareness and knowledge.

Epidemiological Characteristics of Risk Factors of Preurolitiasis and Urolitiasis in Farmers’ Population

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The farmer population was isolated by the absolute selection, in the climatic conditions of the Fergana Valley (2551). Of these, 2478 (men – 1270 and women – 1208) were fully examined. Participation in the study was 96.6 percent. The prevalence of common risk factors in a farmer population using epidemiological, survey, biochemical, and instrumental methods are characterized by high rates and have gender–age characteristics. Risk factors vary sharply with age and increase. Farmers have developed inconsistent epidemiological conditions predisposing them to pre–urolithiasis and urolithiasis, and hence their correction leads to success in primary and secondary prevention.

Problems of Distribution and Pathophysiology of Gastroesophageal Reflux Disease

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This article provides an overview of the literature data on the problem of the prevalence of gastroesophageal reflux disease. Some pathophysiological aspects of this pathology are analyzed. The authors conclude that gastroesophageal reflux disease is a common clinical problem that affects millions of people around the world, according to some reports, up to 25–30% of the adult population is affected by it. Patients are recognized by both classic and atypical symptoms. GERD is associated with lifestyle factors, in particular obesity and tobacco smoking, which also threatens overall health.