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Abiotic environment usually influence the physiological properties of plants, which consequently affect its growth and yield. The research aims to determine the effect of combined integrated fertilizers on the physiological and agronomic character of Aloe vera plants. The experiment was laid out in RCBD, with three replications. Treatments were factorial combinations of cow manure rate (30 and 45 t ha^-1) and humic nitrogen of eight levels i.e. urea, AS, NPK fertilizer, KNO₃, humic urea, humic AS, humic NPK, and humic KNO₃. Observed variables include physiological and agronomic component of plants. Data were subjected to ANOVA followed by DMRT at 5% significance level. There were significant interaction effect between manure rates and nitrogen sources upon all variables measured. Highest values of stomata index and density were achieved by the combined effect of manure rate of 30 t ha^-1 with urea, while manure rate of 45 t ha^-1 with humic urea resulted the highest value of stomata aperture. Increase in all physiological as well as agronomical characters were achieved by manure of 30 and 45 t ha^-1 with the addition of humic urea.