Articles

Antioxidant Properties and Antibacterial Activity of Breadfruit (Artocarpus altilis) Bark and Leaf Extract against Staphylococcus Aureus and Escherichia Coli

/in /by

This study comprehensively investigated the antioxidant properties and antibacterial activity of breadfruit (Artocarpus altilis) bark and leaf extract against two common bacterial strains, Staphylococcus aureus, and Escherichia coli. The objective was to assess the potential therapeutic applications of breadfruit extract in combating bacterial infections caused by these organisms. The researchers employed an experimental research design, utilizing controlled experiments to evaluate the effects of breadfruit extract on the target bacteria. Both the bark and leaf parts of the breadfruit plant were examined in the study.  The extracts were subjected to analysis to identify and quantify the presence of beneficial compounds. The analysis revealed the presence of various compounds, including but not limited to Phenolic Acid and Flavonoids, which are known for their potential health benefits and antioxidant properties. These compounds were found to be present in relatively high concentrations, suggesting the potential of breadfruit extract as a source of natural antioxidants. In terms of antibacterial activity, the breadfruit leaf extract exhibited promising results by demonstrating significant inhibitory effects against both Staphylococcus aureus and Escherichia coli. In contrast, the bark extract showed limited effectiveness against Escherichia coli but displayed some inhibitory activity against Staphylococcus aureus. These findings suggest that breadfruit extract may have potential as a natural antimicrobial agent, particularly in combating Staphylococcus aureus infections.

Teratogenic Risk Potentiality of Blue Ternate (Clitoria ternatea) Leaf Extract Using Chorioallantoic Membrane (CAM) Assay: Phase One

/in /by

The study implemented a descriptive classic experimental design within a laboratory, utilizing the Chorioallantoic Membrane (CAM) assay to investigate the teratogenic potential of Blue Ternate (Clitoria ternatea) leaf extract using the different extract concentrations, and the phytochemical analysis screening unveiled the presence of flavonoids, saponins, tannins, alkaloids, and steroids in the leaves. The primary objectives encompassed the assessment of teratogenicity at various extract concentrations, comparing results with controls, and exploring the plant’s impact on embryonic development. While no significant differences emerged in primary and secondary blood vessels among treatments, a conspicuous variation in tertiary blood vessels indicated potential teratogenic effects at specific concentrations. Nevertheless, the study concluded that Clitoria ternatea exhibits promising therapeutic attributes. Recommendations include the implementation of public awareness programs elucidating the health benefits of Blue Ternate and further investigations into refining, storage practices, and potential teratogenicity in other plant parts. These insights, of considerable value to medical practitioners and future researchers, underscore the importance of caution and consultation, especially for pregnant individuals. In summary, the research significantly contributes to understanding Blue Ternate’s safety profile, presenting avenues for future exploration. The emphasis on careful consideration in medicinal applications, particularly during pregnancy, reinforces the need for responsible and informed decision-making in healthcare practices.