Articles

MPOX (Monkeypox): Current Epidemiology, Clinical Manifestations, and Advances in Treatment and Prevention Strategies

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MPOX (formerly known as monkeypox) has emerged as a significant public health concern in recent years, necessitating a comprehensive understanding of its epidemiology, clinical manifestations, treatment options, prevention strategies, and global health impact. This literature review synthesizes the latest data on the spread and incidence of MPOX, with a focus on geographic distribution, affected populations, and emerging trends in transmission. The clinical presentation of MPOX, including symptoms, disease progression, and complications, is explored, with particular attention to variations across different demographics. Recent advances in the treatment of MPOX are analyzed, covering current antiviral therapies, the role of supportive care, and the potential of new treatments under investigation. Prevention strategies are also examined, highlighting the effectiveness of vaccination efforts, public health measures, and containment and control strategies. The review further considers the broader impact of MPOX on global health, discussing its implications for public health policy and pandemic preparedness. Through this comprehensive analysis, the review aims to provide a robust foundation for understanding MPOX and inform future research, clinical practice, and public health initiatives.

Acinetobacter Baumannii: An Emerging Threat to Public Health – A Review of Literature

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Background: Acinetobacter baumannii is a microbe that is fast becoming a danger or threat to public health. Studies have described a rapidly changing epidemiology of the opportunistic pathogen and credited it with increasing importance in the community and healthcare-associated infections. The threat of A. baumannii is considered to be of public health significance due to its recent association with increased length of hospital admission, increased mortality, and morbidity, particularly among patients in the intensive care units. The objective of this review is to highlight the characteristics of this emergent pathogen to better understand and curtail it.

Methodology: This review comprises a literature search of chapters in books and journals which gives an insight into the peculiarities of A. baumannii. It centers on evolving pathogenesis, epidemiology, antimicrobial susceptibility, laboratory investigations, the molecular basis of resistance, and management of infections caused by the pathogen.

Conclusion: Due to the public health significance of the pathogen, there is an urgent call for increased vigilance and improved knowledge/research-driven approaches to the diagnosis and management of A. baumannii infections.

Epidemiological Characteristics of Risk Factors of Preurolitiasis and Urolitiasis in Farmers’ Population

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The farmer population was isolated by the absolute selection, in the climatic conditions of the Fergana Valley (2551). Of these, 2478 (men – 1270 and women – 1208) were fully examined. Participation in the study was 96.6 percent. The prevalence of common risk factors in a farmer population using epidemiological, survey, biochemical, and instrumental methods are characterized by high rates and have gender–age characteristics. Risk factors vary sharply with age and increase. Farmers have developed inconsistent epidemiological conditions predisposing them to pre–urolithiasis and urolithiasis, and hence their correction leads to success in primary and secondary prevention.