Articles

A Study on Dispersion Characteristics for Inverted Microstrip Lines

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Inverted microstrip lines are studied for their dispersion characteristics for three different values of permittivity of the substrate using Galerkin Technique in Spectral Domain. This structure is very much useful as the current strip is attached at the lower surface of the dielectric substrate. Therefore it is rarely exposed to the outer medium results no effect due to external hazards and almost zero possibility to expose to electro- magnetic interference. Basis functions for the unknown strip current are chosen according to the ones specified in [1]. Basis functions in [1] were for slot magnetic currents and consequently they are modified for the particular problem by considering the modified boundary conditions for Maxwell’s field equations for this structure. For the theoretical development the Fourier transformation of the basis functions from space domain to spectral domain are considered. Variation of effective permittivity with available dielectric thickness has also been studied and the result shows a saturating tendency with increase in dielectric thickness.

A Brief Review on Solubility Enhancement Techniques with Drug and Polymer

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The process of a solid dissolving in a liquid phase to create a homogenous mixture is known as solubility. A crucial factor in getting the right quantity of drug into the bloodstream to show a pharmacological effect is solubility. The main issue in developing formulations for new chemical entities as well as for the creation of generics is low water solubility. More than 40% of novel chemical entities (NCEs) created in the pharmaceutical sector are essentially water insoluble. For formulation scientists, solubility is a significant challenge. Any medicine that is to be absorbed at the absorption site must be there in solution form. The solubility of pharmaceuticals that are poorly soluble can be improved using a variety of approaches, such as complexation, salt formation, particle size reduction, crystal engineering, salt formation, solid dispersion, and the like. The choice of a solubility-improving technology is influenced by pharmacological properties, absorption sites, and the requirements for the dosage form. This review article’s goal is to improve bioavailability and promote effective absorption.