Articles

Phytomedicinal Potential of “Dimocarpus Longan Lour.” as an Essential Nutraceutical

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For many centuries Longan (Dimocarpus longan Lour.) a native plant of Northeastern India, and Southeast Asia has been used for its nutraceutical properties. The phytochemicals constituents include carbohydrates, proteins, polysaccharides, vitamin C, polyphenols, that exhibit innumerable biological properties. It is essential to review the immunomodulatory, antioxidant, and phytomedicinal potential with the aim to provide a comprehensive information for future development of longan as an essential nutraceutical. Longan is in great demand as various food products viz dried pulp, frozen, fresh, and processed as jam, drinks, wine and canned fruit. The key biological activities of longan pericarp are tyrosinase inhibitory, antioxidant, anti-inflammatory, immunomodulatory, anti-glycated, anti-cancer, memory-increasing impact, and other parameters that have a significant contribution to human health.

Thiamethoxam Induced Oxidative Stress and Histopathological Alterations in Male Patients

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Thiamethoxam is one of the second-generation neonicotinoids, a new class of insecticides. The study was designed to investigate the effect of thiamethoxam on fertility in bucks. For this purpose, sixteen male adult male chinchilla rabbits were divided in two groups. Thiamethoxam intoxicated group was treated with thiamethoxam at dose of 250 mg/Kg body weight for 3 months. Semen analysis revealed distinct changes in sperm characteristics including significant decrease in sperm motility (both mass and individual) and sperm count. In addition, significant increase in dead spermatozoa and sperm deformities. Moreover, elevation in testicular concentration of MDA and GST was significant. GSH was significantly decreased. Degeneration and necrosis of spermatogenic cells with intertubular edema and vacuolations in seminiferous tubules were the major observed histopathological changes in the testis of intoxicated animals. In conclusion, thiamethoxam administration for 3 months induced significant decrease in fertility and oxidative stress in the reproductive system of adult male.

Grapes (Vitis Vitaceae) – Potent Medicinal Fruit Serves as a Source of Antioxidants and Antibacterial Agent

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In plant kingdom, medicinal plants are main important resource for a variety of drug like emetics, anti-cancer and antimicrobials. Medicinal herbs are highly cultured in India, which includes more than 2000 species are present. Grapes are soft fruit crop belongs to the Family of Vitaceae and Genus of Vitis. Grapes contain excellent source of nutritional values such as vitamins, minerals, proteins and carbohydrate. In this present work, various phytochemical constituents of grapes were identified in different extracts (Ethanol, Acetone and Aqueous). These phytochemicals are used for the treatment of several diseases. The antioxidant property of different extracts of grapes shows better result. The ellagic acid and the natural phenolic antioxidants were also identified. The antimicrobial activity of various grapes extract shows better result against Enterococcus and E.coli sps. Finally, the grape fruit is a wonderful antioxidant and antimicrobial agent.