Articles

Alternatives Methods for Treatment of Allergic Rhinitis, Alzheimer’s disease and Hypertension

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In Thailand, there are a variety types of Thai herbs. After gathering the information of the extraction methods and properties of herbs, it can be seen that some herbs can be used in treating and inhibiting diseases that have high incidence rate in Thailand such as allergies, Alzheimer’s diseases and hypertension. The extraction of herbs including ginger, fingerroot, red galingale, spinach, garlic and hibiscus have abilities to treat and inhibit diseases that include high incidence rate in Thailand. The article provides information about chronic diseases and medications for treatment, including data on prices, types and their mechanisms of action. Additionally, it outlines details on herbal extracts, highlighting the effects of extraction on patient’s’ symptoms. Finally, the article offers recommendations for patients to select the best treatment method by presenting the advantages and disadvantages of both medications and herbal extracts. Overall, the article emphasizes the importance of choosing the best treatment option for the    well-being of the patients’ body system.

Advancements in Alzheimer’s Disease: Emerging Therapies, Lifestyle Modifications, and Early Intervention Strategies

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: Alzheimer’s disease (AD), the most prevalent form of dementia, represents a major global health challenge, affecting over 45 million people worldwide with projections to triple by 2050 [1]. This progressive, irreversible neurodegenerative disease leads to cognitive decline, behavioural changes, and a significant socioeconomic burden [2]. Despite extensive research into its complex pathophysiology, involving beta-amyloid plaques and tau protein tangles, the exact causes remain a mix of genetic, environmental, and lifestyle factors [3]. Current treatments primarily focus on symptom management, as no cure exists [4]. This literature review synthesises recent advancements in Alzheimer’s research, exploring new pharmacological treatments, emerging therapies, and the efficacy of prevention strategies. It particularly examines how lifestyle modifications and risk factor management influence disease progression. The review highlights the potential of early intervention in at-risk individuals, aiming to prevent significant neuronal damage before clinical symptoms appear. It discusses the impact of various lifestyle factors such as diet, exercise, mental and social engagement, and cardiovascular health on AD risk. Understanding these connections is crucial, given the ageing population and rising prevalence of AD. This review aims to inform better clinical practices and health policies, potentially reducing Alzheimer’s impact and guiding healthcare professionals, researchers, and policymakers in effective interventions. Ultimately, these insights could substantially alleviate the socioeconomic burden of Alzheimer’s disease and improve public health outcomes.

The Potential Presence of Microplastics in Daily Food and Beverage Consumption May Lead to Alzheimer’s disease in The Thai Population

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Environmental issues have become a global crisis. The amount of plastic used has relentlessly increased due to its advantages such as low cost production, lightweight, strength and durability. However, high usage of plastic contributes to microplastics, which are small particles that are difficult to detect and may be found in daily food and beverage consumption. Consequently, it is prone to accumulate in our body and affect our organs, including the brain. From recent studies, there are some possibilities that microplastics exposure can promote human brain damage, including Alzheimer’s. Due to microplastic concerns, this study aims to find out the relation between microplastics in daily food and beverage consumption and Alzheimer’s disease in the Thai population by collecting the responses (509 participants) through a questionnaire. The questionnaire uses Likert scales to evaluate the quantities of daily microplastics consumption, packaging, and Alzheimer assessment. As a result, the data revealed that microplastics consumption has a link to the risk of developing Alzheimer’s disease. We show that microplastics consumption and plastic containers are positively correlated for the Thai population. Consequently, in the course of time, it can lead to other causes of Alzheimer’s disease diagnosed when microplastics are accumulated in the human body. Moreover, it can raise social awareness through campaigns or policies on plastics used which have to be immediately reduced.

The Correlation between Breakfast Consumption and the Probability of Developing Alzheimer’s Disease in Bangkok Population

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Alzheimer’s disease, which is the most common form of dementia, is known to be widely prevalent in the worldwide population, including Thailand. The incidence of this illness in Thailand is increasing rapidly and is expected to reach a million by 2030 (Doungkaew & Taneepanichskul, 2014). We are concerned that this rise is caused by the trend during these modern days, where skipping breakfast is becoming more popular due to time constraints. Hence, we conducted a survey research by providing questionnaires to 180 individuals of all ages across Bangkok, asking for their frequency in consuming breakfast per week and their likelihood in having Alzheimer’s. This was done through an online platform, Google Form. To test whether the two aforementioned variables are correlated with one another, Statistical Product and Service Solution (SPSS) program version 29 was used for data analysis. One-Way ANOVA (F-test) was used to determine the significance between age group and the risk of getting Alzheimer’s. The result showed that age is a significant factor which can promote the illness. Age 41 and above tend to have a stronger probability in developing the disease because of the easier spread of a protein called tau-protein, which is involved in causing Alzheimer’s disease (Wegmann et al., 2019). Pearson’s correlation test has shown that there is a negative correlation between the frequency of breakfast consumption and the risk of developing Alzheimer’s disease. This is likely due to  low blood sugar levels and lack of beneficial nutrients contained in breakfast . In the future, we hope that this research could be beneficial to other people by raising awareness on this particular topic regarding the importance of frequency of breakfast consumption in reducing the risk of developing Alzheimer’s disease.

Alzheimer’s disease: Prevention Strategy

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Alzheimer’s disease (AD) is one of the age-related infections which can develop to Dementia and nowadays both pervasiveness and rate of dementia rise considerably with propelling age Aβ plaques are commonly found in Alzheimer’s patients. neurofibrillary tangles are irregular growth of protein in the brain. Paul Block and George Mannesco believe that Aβ plaques exist, after they discovered circular buildup. AD is eventually caused by neuronal malfunction and death. Aβ cellulose bodies are considered to be less poisonous than Aβ oligomers. A union of blood pressure in adulthood will increase their risk of dementia and Alzheimer’s disease. In the research they found out that old people with 75+ years and the following period are having more risk of dementia and AD. BMI has a bifacial association with dementia and AD has several studies. Due to the uncertain pathophysiological mechanism of Alzheimer’s disease, it is crucial for selecting a precise target population, need for a large sample size, and high cost of the prevention research, it has been a main issue to conduct primary prevention trials. Commonly, healthy seniors are a primary target demographic. Non-pharmacological treatments are helping the patient by enhancing a protective lifestyle like doing physical exercise and a healthy diet. Biomarkers have a priority role to design which group will get in preventative trials, a higher risk of progression of dementia will cut down the studies, however it will decrease the general public’s ability to find the entire community. Primary prevention will evade illness and accomplice pathologies before they arise. Additionally, secondary prevention contains screening to detect disease in its early stages. Tertiary prevention is treating an illness to avoid complex injuries and disability. In a research study, the use of drugs, vitamins, or lifestyle treatments can prevent Alzheimer’s disease, according to the natural definition term the outcome can be a lot of different paths. The possibility of clinical research of AD prevention is full of obstacles.