Abstract :
For many centuries Longan (Dimocarpus longan Lour.) a native plant of Northeastern India, and Southeast Asia has been used for its nutraceutical properties. The phytochemicals constituents include carbohydrates, proteins, polysaccharides, vitamin C, polyphenols, that exhibit innumerable biological properties. It is essential to review the immunomodulatory, antioxidant, and phytomedicinal potential with the aim to provide a comprehensive information for future development of longan as an essential nutraceutical. Longan is in great demand as various food products viz dried pulp, frozen, fresh, and processed as jam, drinks, wine and canned fruit. The key biological activities of longan pericarp are tyrosinase inhibitory, antioxidant, anti-inflammatory, immunomodulatory, anti-glycated, anti-cancer, memory-increasing impact, and other parameters that have a significant contribution to human health.
Keywords :
Antioxidants., bioactivities, Dimocarpus longan, flavonoids, polyphenols., polysaccharidesReferences :
- Morton, J. In: Morton, J.F. and Miami, F.L.(Eds). Fruits of warm climates. 1987 pp. 259–262. http://www.hort.purdue.edu/newcrop/morton/longan.html
- Shahrajabian, M. H., Sun, W. and Cheng, Q. Modern pharmacological actions of Longan fruit and their usages in traditional herbal remedies. J. Med. Plants Stud., 7(4), 2019, pp. 179-185.
- Wangcharoen, W. Development of dried chewy longan arils. Maejo Int J Sci Technol., 7(03), 2013, pp 467-477. http://dx.doi.org/10.14456/mijst.2013.38
- Zhang, X., Guo, S., Ho, C., and Bai, N. Phytochemical constituents and biological activities of longan (Dimocarpus longan) fruit: a review. Food Sci. and Human Wellness, 9(2), 2020, pp. 95-102. https://doi.org/10.1016/j.fshw.2020.03.001
- Pham VT, Herrero M, Hormaza JI (2016) Fruiting pattern in longan (Dimocarpus longan) from pollination to aril development. Ann Appl Biol. Article in Press, First published: 11 July. DOI: 10.1111/aab.12306
- Yang, E. Y., Han, Y. S. and Sim, K. H. Characterization of nutritional, physiochemical, and mineral compositions of aril and seed of longan fruit (Dimocarpus longan). International Food Research Journal, 28(1), 2021, pp. 91 – 101.
- Menzel, C.M., Watson, B.J., Simpson, D.R. Longan: a place in Queensland,s horticulture? Qld Agric J. 115, 1989, pp. 251-265.
- Ripa, F.A., Haque, M. and Bulbul, I.J. In vitro antibacterial, cytotoxic and antioxidant activities of plant Nephelium longan. Pak J Biol Sci., 13(1), 2010, pp.22-27.
- Qiu, D.L. Longan Production and Research in China. Acta Hortic. 1029, 2014, pp.39-46.
- Rakariyatham, K., Zhou, D., Rakariyatham, N. and Shahidi, F. (2020) Sapindaceae (Dimocarpus longan and Nephelium lappaceum) seed and peel by-products: Potential sources for phenolic compounds and use as functional ingredients in food and health applications. J. Funct. Foods.67, 2020, pp103846.
- Chen, J.Y., Xu, Y.J., Ge, Z.Z., Zhu, W., Xu, Z. and Li, C.M. Structural elucidation and antioxidant activity evaluation of key phenolic compounds isolated from longan (Dimocarpus longan) seeds. J. Funct. Foods. 17, 2015, pp.872-880. https://doi.org/10.1016/j.jff.2015.06.028
- Li, L., Xu, J., Mu, Y., Han, L., Liu, R., Cai, T. and Huang, X. Chemical characterization and anti-hyperglycaemic effects of polyphenol enriched longan (Dimocarpus longan) pericarp extracts. J. Funct. Foods. 13, 2015, pp.314-322.
- Khan, S.A., Liu, L., Lai T, Zhang, R., Wei, Z., Xiao, J., Deng, Y. and Zhang, M. (2018) Phenolic profile, free amino acids composition and antioxidant potential of dried longan fermented by lactic acid bacteria. J. Food Sci. Technol., 55, 2018, pp.4782-4791.
- Zhang, L.Y., Ye, D., Lou, Z.H. Inhibitory effects of aqueous extract from longan (Dimocarpus Longan) leaves on kidney calculi. Modern Food Sci. Technol. 34(2), 2018, pp.25-31.
- Sodchit, C., Kongbangkerd, T. and Phun, W.N. Prevention of enzymatic browning of postharvest longan fruit by N-acetyl-L-cysteine and 4-hexylresorcinol. Songklanakarin J Sci Technol. 30(1), 2008, pp.31-35.
- Rashed, K.N. and Fouche, G. Anticancer activity of Dimocarpus longan leaf extracts in vitro and phytochemical profile. Greener J. Med. Plant Res. 1(1), 2013, pp. 001-005.
- Rashed, K., Luo, M.T., Zhang, L.T. and Zheng, Y.T. (2013) Anti-HIV-1 activity of Dimocarpus longan Lour. extracts and the main chemical content. Global J. Microbiol. Biochem. 1, 2013, pp. 1-7.
- Lal, N., Sahu, N., Jayswal, D.K., Diwan, G. and Tandon, K. Traditional, Medicinal and Nutraceutical Values of Minor Fruit: Longan. Curr. J. Applied Sci. Technology. 39(41), 2020, pp 59-70. http://dx.doi.org/10.9734/cjast/2020/v39i4131120
- Varzakas, T., Zakynthinos, G. and Verpoort, F. Plant Food Residues as a Source of Nutraceuticals and Functional Foods. Foods, 5, 2016, pp.1-32. doi:10.3390/foods5040088
- Yi, Y., Wang, H., Zhang, R., Min, T., Huang, F., Liu, L. and Zhang, M. Characterization of polysaccharide from longan pulp as the macrophage stimulator. RSC Adv. 5, 2015, pp. 97163-97170.
- Lin, C.C., Chung, Y. C. and Hsu, C. P. Potential roles of longan flower and seed extract for anti-cancer. World J. Exp. Med. 2(4), 2012, pp. 78-85. https://doi.org/10.5493%2Fwjem.v2.i4.78
- Khatun, M. M., Karim, M. R., Molla, M. M., Khatun, M. M. and Rahman, M. J. Study of the physic-chemical characteristics of longan (Euphoria longana) germplasm. Bangladesh J. Agril. Res. 37(3), 2012, pp.441-447.
- Yang, B., Jiang, Y., Shi, J., Chen, F. and Ashraf, M. (2011) Extraction and pharmacological properties of bioactive compounds from longan (Cimocarpus longan) fruit-A review. Food Res. Int. 44, 2011, pp.1837-1842.
- Florenly, F. E., Aziz, H. and Syafrizayanti, Z. R. The effect of Cr (VI) in the kidney of experimental rats and utilization of longanpeel fruit (Dimocarpus longan) as renal protector in dentistry. Der Pharma Chemica. 8(16), 2016, pp.144-148.
- Ripa, F. A., Haque, M., Bulbul, I. J., Al-Sharmin, A., Begum, Y. and Habib, A. Screening of central nervous system (CNS) depressant and antinociceptive activities of methanolic extracts of the peel and seed of Nephelium longan Afr. J. Pharm Pharmacol. 6(11), 2012, pp.848-854.
- Zhang, R., Khan, S. A., Lin, Y., Guo, D., Pan, X., Liu, L., Wei, Z., Zhang, Y., Deng, Y., and Zhang, M. Phenolic profiles and cellular antioxidant activity of longan pulp of 24 representative Chinese cultivars. Int. J. Food Prop. 21(1), 2018, pp.746-759.
- Son, Y., Lee, E. M., Lee, D.Y., Lee, J. H., Oh, S. Longan fruit increase bone mineral density in zebrafish and ovariectomized rat by suppressing RANKL-induced osteoclast differentiation. Phytomedicine. 59, 2019, pp.152910.
- Yi, Y., Liao, S.T., Zhang, M.W., Shi, J., Zhang, R.F., Deng, Y.Y. and Wei, Z. C. (2011) Physiochemical characteristics and immunomodulatory activities of three polysaccharide-protein complexes of longan pulp. Molecules. 16, 2011, pp. 6148-6164.
- Chung, Y. C., Lin, C. C., Chou, C. C. and Hsu, C. P. The effect of longan seed polyphenols on colorectal carcinoma cells. European Journal of Clinical Investigation. 40,2010, pp.713−721. https://doi.org/10.1111/j.1365-2362.2010.02322.x
- Zhang, Y., Gao, B., Zhang, M. W., Shi, J. and Xu, Y. J. Headspace solid-phase microextraction-gas chromatography–mass spectrometry analysis of the volatile components of longan (Dimocarpus longan). Eur. Food Res. Technol. 229, 2009, pp. 457-465.
- Nair, S.S., Mathew, M. and Sreena, K. Formulation and evaluation of herbal cream containing Curcuma longa. International Journal of Pharmaceutical and Chemical Sciences. 4, 2012, 1362-68.
- Zhong, K., Wang, Q., He, Y. and He, X. Evaluation of radicals scavenging, immunity modulatory and antitumor activities of longan polysaccharides with ultrasonic extraction on in S180 tumor mice models. International Journal of Biological Macromolecules, 47(3), 2010, pp.356-360. https://doi.org/10.1016/j.ijbiomac.2010.05.022
- Park, S. J., Park, D. H., Kim, D. H., Lee, S., Yoon, B. H., Jung, W. Y., Lee, K.T., Cheong, J. and Ryu, J.H. The memory-enhancing effects of Euphoria longan fruit extract in mice. Journal of Ethnopharmacology, 128, 2010, pp.160−165. https://doi.org/10.1016/j.jep.2010.01.001
- Sherine, G., Siddharth, V. B., Erich, A. L., Irfan, S. A., Atiya, A., Brian, T. C., Kenneth, L. W. Cytotoxicity screening of Bangladeshi medicinal plant extracts on pancreatic cancer cells. BMC Complementary and Alternative Medicine. 2010, pp.10:52.