Abstract :
This article provides an overview of the literature data on the problem of the prevalence of gastroesophageal reflux disease. Some pathophysiological aspects of this pathology are analyzed. The authors conclude that gastroesophageal reflux disease is a common clinical problem that affects millions of people around the world, according to some reports, up to 25–30% of the adult population is affected by it. Patients are recognized by both classic and atypical symptoms. GERD is associated with lifestyle factors, in particular obesity and tobacco smoking, which also threatens overall health.
Keywords :
Complications, Endoscopy, Gastroesophageal reflux disease, GERD, GERD pathophysiology, Prevalence, Reflux esophagitis, Risk factors.References :
1. Baulin V.A. Pathogenetic substantiation of a new method of surgical treatment of gastroesophageal reflux disease and hiatal hernia / V.A. Baulin, O.A. Baulina, N.S. Sigaeva // Practical medicine. – 2014. – T:. 30, No. 2. – c. 144–152.
2. Evsyutina Yu.V. A new look at the problem of gastroesophageal reflux disease refractory to treatment with proton pump inhibitors / Yu.V. Evsyutina, A.S. Trukhmanov // Ros. magazine gastroenterology, hepatology, coloproctology. – 2014. – No. 5. – p. 4–9.
3. Ivashkin V.T., Maev I.V., Trukhmanov A.S. and other Recommendations of the Russian Gastroenterological Association for the diagnosis and treatment of gastroesophageal reflux disease // Russian Journal of Gastroenterology, Hepatology, Coloproctology. – 2020. – T:. 30, No. 4. – c. 70–97.
4. Karpitsky A.S. Videolaparoscopic fundoplication as a method for correcting insufficiency of the lower esophageal sphincter / A.S. Karpitsky, G.A. Zhurbenko, A.M. Shestyuk // News of Surgery. – 2013. – T:. 21, No. 2. – c. 94–97.
5. Kozlova N.M., Kalinovskaya I.Yu., Klevtsova O.V. Erosive esophagitis in GERD associated with nocturnal reflux and reduced levels of adiponectin / General question of world science. Collection of scientific papers. Ed. SIC “Science Russia”, 2021, p. 61–66.
6. Lazebnik L.B., Bordin D.S., Masharova A.A. Long-term therapy with proton pump inhibitors: a balance of benefits and risks. Experimental and Clinical Gastroenterology. – 2010. – No. 9. – c. 3–8.
7. Maev I.V., Barkalova E.V., Ovsepyan M.A. Possibilities of impedancemetry and high-resolution manometry in the management of patients with refractory gastroesophageal reflux disease // Therapeutic archive. – 2017. – T. 89, No. 2. – p. 76–83.
8. Morozov S.V. The role of dietary fiber deficiency in the development of manifestations and course of gastroesophageal reflux disease / SV. Morozov, Yu.A. Curly, M.D. Kukushkin // Ros. magazine gastroenterology, hepatology, coloproctology. – 2013. – No. 1. – c. 6–11.
9. Plotnikova E.Yu., Sukhikh A.S., Gracheva T.Yu., Vologzhanina L.G. Clinical efficacy of rabeprazole. Medical alphabet, 2017, 9 (306), p. 40–46.
10. Ryzhkova O.V. Gastroesophageal reflux disease: a textbook. – Irkutsk: IGMU, 2020. -p. 64.
11. Semikina T.M., Kunitsyna M.A., Kashkina E.I., Zhukova E.V. Comprehensive assessment of the risk and mechanisms of development of gastroesophageal reflux disease against the background of obesity // Practical Medicine. – 2018. – No. 2 (113). – c. 41–46.
12. Skvortsov M.B. Clinical and anatomical features of reflux esophagitis and their role in the rationale and choice of treatment tactics / M.B. Skvortsov, O.M. Aleksandrov // Bulletin of the East Siberian Scientific Center of the Siberian Branch of the Russian Academy of Medical Sciences. – 2012. – T:. 86, No. 4. – c. 91–92.
13. Starostin B.D. Gastroesophageal reflux disease. Epidemiology, risk factors // Gastroenterology. – St. Petersburg, 2014. – No. 1. – c. 2–14.
14. Chernousov A.F., Khorobrykh T.V., Vetshev F.P. Repeated antireflux operations // Bulletin of Surgical Gastroenterology. – 2011. – No. 3. – c. 4–15.
15. Chernousov A.F. Mistakes and complications of antireflux surgery / A.F. Chernousov, T.V. Khorobrikh, F.P. Vetshev // Bulletin of Surgical Gastroenterology. – 2014. -№ 1–2. – c. 5–16.
16. Shishko V.I. Gastroesophageal reflux disease: classification, diagnosis, principles of treatment (literature review, part 2) / V.I. Shishko, Yu.Ya. Petrulevich // Journal of Grodno State Medical University. – 2015. – T. 50, No. 2. – p. 15–23.
17. Shulpekova Yu.O. Gastroesophageal reflux disease: clinical and pharmacological aspects / Yu.O. Shulpekova, V.T. Ivashkin // Russian honey. magazine – 2002. – No. 4. – p. 200–205.
18. Bazerbachi F, Krishnan K, Abu Dayyeh BK. Endoscopic GERD therapy: A primer for the transoral incisionless fundoplication procedure. Gastrointest Endosc. 2019, 90 (3), – p. 370–383.
19. Gong E.J, Park C.H, Jung D.H, Kang S.H, Lee J.Y, Lim H, Kim D.H. Endoscopic Therapy And Instrument Research Group Under The Korean Society Of Neurogastroenterology And Motility. Efficacy of Endoscopic and Surgical Treatments for Gastroesophageal Reflux Disease: A Systematic Review and Network Meta–Analysis. J Pers Med. 2022 April 12, 12 (4), – p. 621.
20. Katz P.O, Gerson L.B, Vela M.F. Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol. 2013, 108, – p. 308–328.
21. Lundell L, Miettinen P, Myrvold H.E, Hatlebakk J.G, Wallin L, Engström C, Julkunen R, Montgomery M, Malm A, Lind T, Walan A; Nordic GERD Study Group. Comparison of outcomes twelve years after antireflux surgery or omeprazole maintenance therapy for reflux esophagitis. Clin Gastroenterol Hepatol. 2009 Dec 7 (12), – p. 1292–1297.
22. McKinley S.K, Dirks R.C, Walsh D, Hollands C, Arthur L.E, Rodriguez N, Jhang J, Abou–Setta A, Pryor A, Stefanidis D, Slater BJ. Surgical treatment of GERD: systematic review and meta-analysis. Surg Endosc. 2021 Aug, 35 (8), – p. 4095–4123.
23. Mittal R.K, Balaban D.H. The esophagogastric junction. N Engl J Med. 1997, 336, –p. 924–932.
24. Richter J.E, Rubenstein J.H. Presentation and epidemiology of gastroesophageal reflux disease. Gastroenterology. 2018, 154, – p. 267–276.
25. Sifrim D, Zerbib F. Diagnosis and management of patients with reflux symptoms refractory to proton pump inhibitors. Gut. 2012, 61, – p. 1340–1354.