Abstract :

Introduction: Odontogenic keratocysts (OKCs) are developmental odontogenic cysts of epithelial origin. The initial terminology for an odontogenic keratocyst (OKC) was “primordial cyst,” as the origin of the lesion was thought to be the tooth primordium. Objective: To determine the frequency of clinical features and radio graphical appearance of odontogenic keratocyst.

Subjects and methods: This Cross Sectional Study was conducted in Akhtar saeed trust hospital Lahore from 2020 to March 2021. A total of 216 patients of both genders with odontogenic keratocysts were included.  Patients with history of basal cell nervous syndrome, Orthokeratinized variant and treated cases were excluded. Clinical features and radio graphical appearance of odontogenic keratocyst was collected as per operational definition. Clinical features were noted under the supervision of a consultant with 3 years’ post fellowship experience. Data was collected and noted.

Results: Age range in this study was from 20 to 40 years with mean age of 29.629±3.87 years, mean weight 72.675±12.99 kg, mean height 1.556±0.10 meters, mean BMI 30.087±5.03 Kg/m², mean duration of complain 8.555±2.49 months and mean pain score was 5.291±1.85. Majority of the patients (61.1%) belongs to 20-30 years age groups. While males were 56.9% as compare to females 43.1%. Pain was seen in 52.8% patients, facial asymmetry 69.4% and root resorption was 9.3%.

Conclusion: It is recommended to the general dental practitioners to have an overview of whole of the stomatognathic system, even if a patient comes for a single tooth problem.

---

Keywords :

Clinical features, Odontogenic keratocysts, Radio graphical appearance.

---

References :

1. Eryilmaz T, Ozmen S, Findikcioglu K, Kandal S, Aral M. Odontogenic keratocyst: an unusual location and review of the literature. Ann Plast Surg. 2009;62(2):210-2.
2. Pindborg JJ, Hansen J. Studies on odontogenic cyst epithelium. Acta Pathol Microbiol Scand. 1963;58:283-94.
3. Hajalioghli P, Ghadirpour A, Ataie-Oskuie R, Kontzialis M, Nezami N. Imaging findings of gorlin-goltz syndrome. Acta Radiol Short Rep. 2015 Jan;4(1):2047981614552294.
4. Avril L, Lombardi T, Ailianou A. Radiolucent lesions of the mandible: a pattern-based approach to diagnosis. Insights Imaging. 2014 Feb;5(1):85–101.
5. Zhu L, Yang J, Zheng JW. Radiological and clinical features of peripheral keratocystic odontogenic tumor. Int J Clin Exp Med. 2014;7(1):300-6.
6. Vij H, Vij R, Gupta V, Sengupta S. Odontogenic keratocyst: a peripheral variant. Nig J Clin Pract. 2011;14(4):504-7.
7. Khan MT, Khan A, Khitab U, Salam A. Odontogenic keratocysts: a clinical and radiographic study. Pak Oral Dent J. 2010;30(1):52-56.
8. Sánchez-Burgos R, González-Martín–Moro J, Pérez-Fernández E, Bur­gueño-García M. Clinical, radiological and therapeutic features of kera­tocystic odontogenic tumours: a study over a decade. J Clin Exp Dent. 2014;6(3):e259-64.
9. Matteson SR. Benign tumors of the jaws. In: White SC, Pharoah MJ, editors. Oral radiology : principles and interpretation. 7^th Louis, Missouri : Elsevier; 2014.p. 378-94.
10. Ahlfors E, Larsson A and Sjogren S. The Odontogenic Keratocyst: A Benign cystic tumor? J Oral Maxillofac Surg 1984;42(1): 10-19.
11. Cawson RA, Binnie WH, Speight P, Barrett AW, Wright JM, Thorogood P. Luca’s pathology of tumors of the oral tissues 5th edition. Churchill livingstone 1998.
12. Vedtofte P, Holmstrup P, Dabelsteen E. Human odontogenic keratocyst transplant in nude mice. Scand J Dent Res 1982;90(4):306–14
13. Stenman G, Magnusson B, Lennartsson B, Juberg-Ode M. In vitro growth characteristics of human odontogenic keratocysts and dentigerous cysts. J Oral Pathol 1986;15(3):143-145
14. Smith G, Mathews JB, Smith AJ, Browne RM. Immunoglobulin-producing cells in human odontogenic cysts. J Oral Pathol 1987;16(1): 45-48.
15. Smith G, Smith AJ and Basu MK. Mast cells in the human odontogenic cysts. J Oral Pathol Med 1989;18(5): 274-278.
16. Kumar V, Cortan R, Robbins S. Basic Pathology. 7th edition; Saunders Company 2003
17. Schottenfeld D, Beebe-DimmerJ. Chronic Inflammation: A Common and Important Factor in the Pathogenesis of Neoplasia. CA Cancer J Clin 2006;56(2);69-83.