Abstract :

Introduction: Cancer is a global public health issue, causing approximately 8.8 million deaths per year. According to the World Health Organization (WHO), the countries that suffer most from the disease are low-income and middle-income countries. Objectives: The main objective of the study is to finding the relationship of smoking and survival rate in oral submucous cancer patients.

Material and methods: This cross sectional study was conducted in Services Hospital, Lahore during 2021. The data was collected from 204 patients. From this sample socio-demographic data such as age, sex, education, marital status, smoking status, and method of hospital admission were analyzed.

Results: The data was collected from 204 patients. Most patients were up to 65-year-old, with no difference in age distribution between the groups. Regarding the type of treatment, nonsmoking patients complied with no treatment, surgery or surgery plus radiotherapy (RT), with RT associated with chemotherapy (CT) being the most common treatment.

Conclusion: It is concluded that we found the significant positive dose-response relationship among smokers on clinical outcome in OSCC patients and that non-smokers were worse prognosis than light smokers. In addition, this effect might differ by treatment method.

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Keywords :

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