Abstract :

The present study was carried out to evaluate the antihyperglycemic property of Terminalia arjuna in streptozotocin-induced type 2 diabetic model rats. To evaluate the antihyperglycemic and antioxidant role of ethanol extract of Terminalia arjuna leaf in rats. Hyperglycemia was induced in rats by single intraperitoneal injection of streptozotocin (STZ, 120mg/kg body weight). Three days after STZ induction, the hyperglycemic rats were treated with a dilution of bark extract of T. arjuna orally at the dose of 1 ml and 2 ml daily for 15 days. The level of blood glucose before meals were measured on every fifth day during the 15-day treatment. Ethanol extract of T. arjuna dose-dependently reduced and normalized blood glucose levels. T.arjuna treatment also significantly increases protein levels. The present study shows that T. arjuna leaf shows remarkable reduction in blood glucose level in STZ-induced diabetic rats. The T. arjuna has an effect in physiological and biochemical processes in rats.

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Keywords :

Antihyperglycemic, streptozotocin, Terminalia arjuna (Combretaceae).

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