Abstract :

The transition from Individual Contributor (IC) to First-Line Manager (FLM) represents a critical career milestone in the highly regulated Indian clinical research sector. Within centralized operational models such as Centralized Monitoring and electronic Trial Master File (eTMF) oversight, FLMs are required to balance technical compliance demands with effective people leadership. Despite the strategic importance of these roles, empirical research capturing direct reports’ perspectives remains limited. This study adopted a qualitative approach informed by grounded theory principles to explore how direct reports perceive managerial behaviors, effectiveness, and challenges in centralized teams. Semi-structured interviews were conducted with nine professionals (n = 9) working across centralized functions in Indian contract research organizations (CROs). Data were analyzed using the constant comparative method to identify recurring patterns in the manager–report relationship. The findings indicate a clear contrast in leadership experiences. Positive direct report perceptions were associated with relational trust, psychological safety, consistent communication, and empowerment. In contrast, negative experiences were linked to technical credibility gaps, communication breakdowns, and perceived favoritism. Reporting duration emerged as an important contextual factor: shorter reporting tenures reflected greater tolerance for managerial learning curves, whereas longer tenures without visible developmental progress were associated with frustration and reduced morale. The study highlights that FLM effectiveness in centralized clinical research teams is a developmental process shaped by relational competence and organizational support. By foregrounding psychological safety as an important enabler of trust and team resilience, this study contributes a bottom‑up perspective to leadership literature within the clinical research industry and offers practical insights for designing interventions that strengthen communication, fairness, and psychologically safe team environments during early managerial transitions.

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Keywords :

Centralized clinical research teams, Direct reports’ perspectives, First-line manager transition, Indian contract research organizations (CROs)., Individual contributor transition to FLM

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References :

1. Agrawal, V., & Bhandar, M. (2026). Building first-line leadership in contract research organizations: Senior leaders’ perspectives on critical transition competencies. International Journal of Current Science Research and Review, 9(1), 426–435. https://doi.org/10.47191/ijcsrr/V9-i1-56
2. Ashforth, B. E., & Mael, F. (1989). Social identity theory and the organization. Academy of Management Review, 14(1), 20–39. https://doi.org/10.2307/258189
3. Bolander, P., Holmberg, I., & Fellbom, E. (2019). Learning to become manager: The identity work of first-time managers. Management Learning, 50(3), 282–301. https://doi.org/10.1177/1350507618820711
4. Cvetkovski, A. (2017). Support for the first-line manager and self-managing teams provided by HR departments. Proceedings of the 9th IBA Bachelor Thesis Conference, Enschede, The Netherlands.
5. Edmondson, A. C. (1999). Psychological safety and learning behavior in work teams. Administrative Science Quarterly, 44(2), 350–383. https://doi.org/10.2307/2666999
6. Glaser, B. G., & Strauss, A. L. (1967). The discovery of grounded theory: Strategies for qualitative research. Aldine.
7. Graen, G. B., & Uhl-Bien, M. (1995). Relationship-based approach to leadership: Development of leader–member exchange (LMX) theory. The Leadership Quarterly, 6(2), 219–247. https://doi.org/10.1016/1048-9843(95)90036-5
8. Kandi, V., & Vadakedath, S. (2023). Clinical trials and clinical research: A comprehensive review. Cureus. https://doi.org/10.7759/cureus.35077
9. Kilroy, J., & Dundon, T. (2015). The multiple faces of front-line managers. Employee Relations, 37(4), 410–427. https://doi.org/10.1108/ER-06-2014-0071
10. Kishnani, J. (2023). Enhancing managerial effectiveness and mitigating early-stage managerial failures. International Journal of Science and Research, 12(10), 926–929. https://doi.org/10.21275/SR231011092123
11. Nachtergaele, S., De Roo, N., Allart, J., De Vriendt, P., Embo, M., & Cornelis, E. (2024). Exploring influencing factors to clinical leadership development: A qualitative study with healthcare professionals in Flemish nursing homes. BMC Health Services Research, 24(1), Article 100. https://doi.org/10.1186/s12913-024-11613-9
12. Nicholson, N. (1984). A theory of work role transitions. Administrative Science Quarterly, 29(2), 172–191. https://doi.org/10.2307/2393172
13. Plakhotnik, M. S. (2017). First-time managers: Increasing chances of success before promotion. Industrial and Commercial Training, 49(3), 132–138. https://doi.org/10.1108/ICT-10-2016-0070
14. Raulgaonkar, H. (2023). Success of the “first-time first-line manager”: Model development and validation. Emerald Open Research, 1(4), Article 45. https://doi.org/10.35241/emeraldopenres.14212.1
15. Rooney, J. A., Gottlieb, B. H., & Newby-Clark, I. R. (2009). How support-related managerial behaviors influence employees. Journal of Managerial Psychology, 24(5), 410–427. https://doi.org/10.1108/02683940910959744
16. Saunders, B., Sim, J., Kingstone, T., Baker, S., Waterfield, J., Bartlam, B., Burroughs, H., & Jinks, C. (2018). Saturation in qualitative research: Exploring its conceptualization and operationalization. Quality & Quantity, 52(4), 1893–1907. https://doi.org/10.1007/s11135-017-0574-8
17. Schall, D. J. (2025). The impact of ineffective leaders on organizational performance. Open Journal of Business and Management, 13(3), 2058–2098. https://doi.org/10.4236/ojbm.2025.133108
18. Sillett, D. (2015). How to support and develop first-time managers? Industrial and Commercial Training, 47(1), 46–50. https://doi.org/10.1108/ICT-06-2014-0040
19. Taylor, S. J., Bogdan, R., & DeVault, M. L. (2015). Introduction to qualitative research methods: A guidebook and resource (4th ed.). Wiley.