Abstract :
Background: Overweight and obesity remain major global health problems and are closely associated with metabolic disorders, including hypercholesterolemia. Elevated total cholesterol levels contribute significantly to the development of atherosclerosis and increase the risk of cardiovascular diseases. In Indonesia, particularly in East Nusa Tenggara, the prevalence of overweight and obesity is relatively high among employees. Moringa oleifera, a locally available plant widely consumed as food, contains dietary fiber and bioactive compounds with antioxidant properties that may influence lipid metabolism.
Objective: This study aimed to evaluate the effect of moringa leaf soup consumption on changes in total cholesterol levels among overweight employees at Nusa Cendana University.
Methods: A pre-experimental study with a one-group pre-test–post-test design was conducted among 27 employees selected using purposive sampling. Participants received moringa leaf soup as an intervention for seven consecutive days. Total cholesterol levels were measured before and after the intervention using capillary blood samples analyzed with a point-of-care testing device. Data were analyzed using a paired sample t-test.
Results: The mean total cholesterol level before the intervention was 190.18 mg/dL, which decreased to 179.22 mg/dL after the intervention. The mean reduction in total cholesterol level was 10.96 mg/dL. Statistical analysis demonstrated a significant decrease in total cholesterol levels following seven days of moringa leaf soup consumption (p = 0.012).
Conclusion: Consumption of moringa leaf soup was associated with a significant reduction in total cholesterol levels among overweight employees at Nusa Cendana University.
Keywords :
Employees, Moringa oleifera, Obesity, overweight, Total cholesterolReferences :
- Sumarni, Anonim T, Supriyo. Lipid profile characteristics (HDL, LDL, total cholesterol, and triglycerides) among individuals with excess nutritional status. Jurnal Lintas Keperawatan. 2023;4(2):312–317.
- Wahyuni T, Diansabila J. Association between body mass index and cholesterol levels among medical students. Muhammadiyah Journal of Nutrition and Food Science. 2020;1(2):54–59.
- World Health Organization. Obesity and overweight. Geneva: World Health Organization; 2020.
- Ministry of Health of the Republic of Indonesia. Indonesian Health Survey 2023. Jakarta: Ministry of Health of the Republic of Indonesia; 2023.
- Tjong SL. Hypertension, lipids, and cholesterol. Jurnal MIPA. 2021;10(1):8–15.
- World Health Organization. Nutrition. Geneva: World Health Organization; 2020.
- Ministry of Health of the Republic of Indonesia. National report of Basic Health Research (Riskesdas) 2018. Jakarta: National Institute of Health Research and Development; 2018.
- Krisnadi AD. Moringa: a super-nutritious plant. Revised edition. 2019.
- Marhaeni LS. Moringa oleifera leaves as functional food and antioxidant source. AGRISIA: Journal of Agricultural Sciences. 2021;13(2).
- Islam Z, Islam SM, Hossen F, Mahtab-ul-Islam K, Hasan MR, Karim R. Moringa oleifera is a prominent source of nutrients with potential health benefits. International Journal of Food Science. 2021;2021:6627265.
- Mendila N, et al. Effect of moringa leaf extract on total cholesterol levels in male Wistar rats with dyslipidemia model. 2025.
- Susanti G. Cholesterol-lowering activity of moringa leaf extract in male Sprague Dawley rats. 2020.
- Marumata C, et al. Effect of moringa leaf juice on cholesterol levels in adults with hypercholesterolemia. 2019.
- Erwinanto, Susanto, Santoso A, Desandri DR, Erika, Sukmawan R, Wicaksono SH, Pintaningrum Y, et al. Indonesian Society of Cardiology guideline for dyslipidemia management. Indonesian Journal of Cardiology. 2022.
- Hanif F, Berawi KN. Literature review: moringa (Moringa oleifera) as a complementary healthy food during the first 1,000 days of life. Jurnal Kesehatan. 2022;13(2):398–407.
- Rode SB, Dadmal A, Salankar HV. Nature’s gold (Moringa oleifera): miracle properties. Cureus. 2022;14(7):e26640.
- Rivai ATO. Identification of bioactive compounds in moringa (Moringa oleifera) leaf extract. Indonesian Journal of Fundamental Sciences. 2020;6(2).
- Putra IWDP, Dharmayudha AAGO, Sudimartini LM. Identification of chemical compounds in ethanolic extract of moringa (Moringa oleifera) leaves. Indonesia Medicus Veterinus. 2016;5(5):464–473.
- Vinca DT, Iqbal M, Triyandi R, Oktarlina RZ. Antibacterial activity of moringa (Moringa oleifera) leaf extract against Staphylococcus aureus. Jurnal Profesi Kedokteran Lampung. 2023;13(4):649–654.
- Adli M. Distribution and diversity of moringa (Moringa oleifera) plants in Malang Regency. Dissertation. Universitas Brawijaya; 2018.
- Ministry of Health of the Republic of Indonesia. Regulation of the Minister of Health No. 41 of 2014 on Balanced Nutrition Guidelines. Jakarta: Ministry of Health of the Republic of Indonesia; 2014.
- Gopalakrishnan L, Doriya K, Kumar DS. Moringa oleifera: a review on nutritive importance and medicinal applications. Food Science and Human Wellness. 2016;5:49–56.
- Mathur M, et al. The role of Moringa oleifera in cholesterol reduction. 2019.

