Abstract :
Background: Maternal anemia remains one of the most common complications during pregnancy and continues to pose a significant public health challenge, particularly in low- and middle-income countries. Reduced hemoglobin concentration during pregnancy may impair oxygen and nutrient transport from mother to fetus, potentially resulting in suboptimal fetal growth and adverse perinatal outcomes, including low birth weight.
Objective: To evaluate the association between anemia in third-trimester pregnant women and the incidence of low birth weight among newborns at Sikumana Primary Health Center.
Methods: This study employed an observational analytic design with a prospective cohort approach. A total of 50 third-trimester pregnant women and their newborns were enrolled. Maternal hemoglobin levels were measured using venous blood samples analyzed in the laboratory, while neonatal birth weight data were obtained from maternal and child health records or birth certificates. Data normality was assessed using the Kolmogorov–Smirnov test, and the relationship between maternal anemia and birth weight was analyzed using Pearson correlation.
Results: The prevalence of anemia among third-trimester pregnant women was 36%, while the incidence of low birth weight was 40%. The most frequently observed erythrocyte morphologies were microcytic hypochromic and normocytic normochromic patterns. Statistical analysis demonstrated a significant association between maternal anemia and low birth weight (p = 0.032), with a moderate correlation strength (r = 0.304).
Conclusion: Anemia in the third trimester of pregnancy was significantly associated with low birth weight among infants delivered at Sikumana Primary Health Center. Strengthening early detection and management of maternal anemia may contribute to improved neonatal outcomes.
Keywords :
Anemia, Low Birth Weight, newborn, pregnancy, primary health careReferences :
- World Health Organization. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Geneva: World Health Organization; 2011.
- World Health Organization. Iron deficiency anaemia: assessment, prevention and control. A guide for programme managers. Geneva: World Health Organization; 2001.
- Proverawati A, Asfuah S. Nutrition in midwifery practice. Yogyakarta: Nuha Medika; 2010.
- World Health Organization. Worldwide prevalence of anaemia 1993–2005: WHO global database on anaemia. Geneva: World Health Organization; 2008.
- Ministry of Health of the Republic of Indonesia. Indonesia Basic Health Research (Riskesdas) 2018. Jakarta: National Institute of Health Research and Development; 2018.
- Sikumana Primary Health Center. Annual report on maternal anemia among pregnant women, 2022. Kupang: Sikumana Primary Health Center; 2022.
- Cunningham FG, Leveno KJ, Bloom SL, et al. Williams obstetrics. 25th ed. New York: McGraw-Hill Education; 2018.
- World Health Organization. Low birth weight: country, regional and global estimates. Geneva: World Health Organization; 2014.
- United Nations Children’s Fund (UNICEF). Low birthweight: country, regional and global estimates. New York: UNICEF; 2019.
- Barker DJP. The developmental origins of adult disease. J Am Coll Nutr. 2004;23(6 Suppl):588S–595S.
- Guyton AC, Hall JE. Textbook of medical physiology. 13th ed. Philadelphia: Elsevier Saunders; 2016.
- Wahyuni W, et al. Association between maternal anemia and low birth weight at Supiori District Hospital. 2022.
- Rahmah R, Karjadidjaja I. Maternal anemia and low birth weight in Pasar Rebo Primary Health Center, East Jakarta. 2020.
- Khairunnisa K, et al. Maternal anemia during pregnancy and low birth weight in several primary health centers in Semarang, Indonesia. 2019.
- Lusi L, et al. Maternal hemoglobin level and birth weight among newborns in Kupang City. 2019.
- World Health Organization. Care of the preterm and low-birth-weight newborn. Geneva: World Health Organization; 2014.
