Title : Urinary Tract Infections as a Trigger for Dementia Progression

Vol 8 No 2 (2025): Volume 08 Issue 02 February 2025

Article Date Published : 10 February 2025 | Page No.: 702-711 | Google Scholar | Crossref doi for this article

Abstract :

Urinary tract infections (UTIs) are one of the infections that occur most frequently among the elderly and are now increasingly recognized as a significant factor in the causation of cognitive decline, particularly among those who had previously experienced dementia. This broad review focuses on epidemiological evidence, underlying pathophysiological mechanisms, and clinical consequences for examining the complex interrelationship between UTIs and dementia. Frequent UTIs have been shown to worsen the symptoms of dementia and accelerate cognitive deterioration due to the induction of systemic inflammation, neuro-inflammation, and disturbances of the blood-brain barrier. Delayed treatment due to diagnostic difficulties in the elderly further exacerbates cognitive effects. Preventive measures associated with alleviation of UTI-related cognitive burden include early detection, efficient management of UTI, and techniques reducing inflammation. It thus emphasizes on integrating multidisciplinary approaches as an improvement pathway towards better results in this highly vulnerable population.

Keywords :

cognitive burden., Cognitive decline, Dementia, Inflammation, urinary tract infection

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Urinary Tract Infections as a Trigger for Dementia Progression. Samudrala Lahari, Y. Sneha, Chitti Sathwika, Meghavath Tharun, T. Rama Rao, 8(2), 702-711. Retrieved from https://ijcsrr.org/single-view/?id=21207&pid=21198

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