Abstract :
The two dimensions currently included in international classifications should include a third defining dimension, regarding to the analysis of intensity of needs relationship to the main parameters of psychoneural information processing, within the so-called processual dimension: – perception and sensory memory, – encoding and categorical grouping, – access of information to permanent memory, and – recovery of information in semantic terminology. These new criteria constitute basic elements governing the neurocerebral process in a global sense, which will allow the persistence or improvement of observable social and restrictive-stereotyped behaviours related to the two dimensions included in the currently classifications.
An exhaustively analysed Case Study in all its evolution over 32 years, has allowed successive comparative analyses regarding the differential phases with the specific autistic diagnosis, whose final results allowed confirming new paradigmatic findings of new paradigmatic definitions of autistic disorder, its differential diagnostic processing and, therefore, the new specific kinds of psychoeducational intervention.
Keywords :
Autistic Spectrum Disorder. New paradigm. Conceptual- propositional. Diagnosis. Intervention pycho- social and educational.References :
- Adorjan, I., Ahmed, B., Feher, V., Torso, M., Krug, K., Esiri, M., … & Szele, F. G. (2017). Calretinin interneuron density in the caudate nucleus is lower in autism spectrum disorder. Brain, 140(7), 2028–2040. https://doi.org/10.1093/brain/awx131
- American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th). American Psychiatric Publishing. https://www.amazon.es/stores/American-Psychiatric-Association/author/B00LZF2ELC?ref=ap_ rdr&isDramIntegrated=true&shoppingPortalEnabled=true
- Amina, S., Falcone, C., Hong, T., Wolf-Ochoa, M. W., Vakilzadeh, G., Allen, E., … & Martinez–Cerdeno, V. (2021). Chandelier cartridge density is reduced in the prefrontal cortex in autism. Cerebral Cortex, 31(6), 2944–2951. https://doi.org/10.1093/cercor/bhaa402
- Ariza, J., Rogers, H., Hashemi, E., Noctor, S. C., & Martinez–Cerdeno, V. (2018). The number of chandelier and basket cells are differentially decreased in prefrontal cortex in autism. Cerebral Cortex, 28(2), 411–420. https://doi.org/10.1093/cercor/bhw349
- Brown, C., Gruber, T., Boucher, J., Rippon, G., & Brock, J. (2005). Gamma abnormalities during perception of illusory figures in autism. Cortex. A Journal Devoted to the Study of the Nervous System and Behavior, 41, 364–376. https://pubmed.ncbi.nlm.nih.gov/15871601/
- Casanova, M. F., Buxhoeveden, D. P., Switala, A. E., & Roy, E. (2002). Minicolumnar pathology in autism. Neurology, 58(3), 428–432. https://doi.org/10.1212/wnl.58.3.428
- Center for Disease Control and Prevention (CDC). (2010). Prevalence of autism spectrum disorders–autism and developmental disabilities monitoring network, United States. Morb Mortal Wkly Rep. 2014; 63(2). https://pubmed.ncbi.nlm.nih.gov/22456193/
- Courchesne, E., Mouton, P. R., Calhoun, M. E., Semendeferi, K., Ahrens-Barbeau, C., Hallet, M. J., … & Pierce, K. (2011). Neuron number and size in prefrontal cortex of children with autism. JAMA, 306(18), 2001–2010. https://doi.org/10.1001/jama.2011.1638
- Dufour, B. D., McBride, E., Bartley, T., Juarez, P., & Martínez–Cerdeño, V. (2023). Distinct patterns of GABAergic interneuron pathology in autism are associated with intellectual impairment and stereotypic behaviors. Autism, 27(6) 1730–1745. DOI: 10.1177/13623613231154053. journals.sagepub.com/home/aut
- Falcone, C., Mevises, N. Y., Hong, T., Dufour, B., Chen, X., Noctor, S. C., & Martinez–Cerdeno, V. (2021). Neuronal and glial cell number is altered in a cortical layer-specific manner in autism. Autism, 25(8), 2238–2253. https://doi.org/10.1177/13623613211014408
- Hadjikhani, N., Zürcher, N. R., Rogier, O., Ruest, T., Hippolyte, L., …. & Lemonnier, E. (2015). Improving emotional face perception in autism with diuretic bumetanide: A proof-of-concept behavioral and functional brain imaging pilot study. Autism, 19(2) 149–157. DOI: 10.1177/1362361313514141
- Hashemi, E., Ariza, J., Rogers, H., Noctor, S. C., & Martinez–Cerdeno, V. (2017). The number of parvalbumin- expressing interneurons is decreased in the prefrontal cortex in autism. Cerebral Cortex, 27(3), 1931–1943. https://doi.org/10.1093/cercor/bhw021
- Hollocks, M. J., Lord, C., Charman, T., Gillian, B., Pickles. A., & Simonoff, E. (2022). Exploring the impact of adolescent cognitive inflexibility on emotional and behavioural problems experienced by autistic adults. Autism, 26(5) 1229–1241. https://doi.org/10.1177/13623613211046160
- Hutsler, J. J., & Zhang, H. (2010). Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders. Brain Research, 1309, 83–94. https://doi.org/10.1016/j.brainres.2009.09.120
- Kang, J. Q., & Barnes, G. (2013). A Common Susceptibility Factor of Both Autism and Epilepsy: Functional Deficiency of GABA [subscript A] Receptors. Journal of Autism and Developmental Disorders, 43(1), 68–79. http://www.springerlink.com.acceso.uvigo.gal
- Kohane, I. S., McMurry, A., Weber, G., MacFadden, D., Rappaport, L., Kunkel, L., … & Churchill, S. (2012). The comorbidity burden of children and young adults with autism spectrum disorders. PLOS ONE, 7(4), Article e33224. https://doi.org/10.1371/journal.pone.0033224
- Lawrence, Y. A., Kemper, T. L., Bauman, M. L., & Blatt, G. J. (2010). Parvalbumin- calbindin-, and calretinin-immunoreactive hippocampal interneuron density in autism. Acta Neurologica Scandinavica, 121(2), 99–108. https://doi.org/10.1111/j.1600-0404.2009.01234.x
- Lord, C., Rutter, M., Dilavore, P. C., Risi, S., Gotham, K., & Bishop, S. L. (2012). Autism Diagnostic Observation Schedule, second edition (ADOS-2). Western Psychological Services. DOI: 10.1007/978-1-4419-1698-3_896
- Maenner, M. J., Shaw, K. A., Baio, J., Washington, A., Patrick, M., DiRienzo, M., … & Dietz, P. M. (2020). Prevalence of autism spectrum disorder among children aged 8 years–Autism and developmental disabilities monitoring network, 11 sites, United States, 2016. MMWR Surveillance Summaries, 69(4), 1–12. https://doi.org/10.15585/mmwr.ss6904a1
- Mizuno, A., Liu, Y., Williams, D. L., Keller, T. A., Minshew, N. J., & Adam, M. (2011). The neural basis of deictic shifting in linguistic perspective-taking in high-functioning autism Just Brain. A Journal of Neurology, 134, 2422–2435. DOI: 10.1093/brain/awr151
- Nardou, R., Yamamoto, S., Bhar, A., Burnashew, Y., Ben–Ari, I., & Khalilov, I. (2011). Phenobarbital but Not Diazepam Reduces AMPA/kainate Receptor ediated Currents and Exerts Opposite Actions on Initial Seizures in the Neonatal Rat Hippocampus. Frontiers in Cellular Neuroscience, 5, 16. https://pubmed.ncbi.nlm.nih.gov/21847371/
- Nardou, R., Yamamoto, S., Chazal, G., Bhar, A., Ferrand, N., Dulac, O., … & Khalilov, I. (2011). Neuronal chloride accumulation and excitatory GABA underlie aggravation of neonatal epileptiform activities by phenobarbital. Brain, 134, 987–1002. https://pubmed.ncbi.nlm.nih.gov/21436113/
- Ojea, M. (2023). Perceptual-behavioural assessment scale: EP-PC-TEA. Lima, Perú. https://libreriaites.com/producto/escala-de-precision-perceptivo-conductual-ep-pc-tea/
- Pizzarelli, R., & Cherubini, E. (2011). Alterations of GABAergic signalling in autism spectrum disorders. Neural Plasticity, 297153 (12 pp.). https://onlinelibrary.wiley.com/doi/10.1155/2011/297153
- Rivière, A. (2002). IDEA: Inventario del Espectro Autista. Facatativá–Cundinamarca: Fundec. https://www.asemco.org/documentos/asemco-idea.pdf
- Rubenstein, J. L. R. (2011). Annual Research Review: Development of the Cerebral Cortex–Implications for Neurodevelopmental Disorders. Journal of Child Psychology and Psychiatry, 52(4), 339-355. http://www.wiley.com.acceso.uvigo.gal/WileyCDA/
- Rutter, M., LeCouteur, A., & Lord, C. (2003). Autism Diagnostic Interview, Revised. Los Angeles: Western Psychological Services. https://link.springer.com/referenceworkentry/10.1007/978-1-4419-1698-3_894
- Schuck, M., & Swanson, Ch. I. (2019). Infantile Spasms: The Role of Prenatal Stress and Altered GABA Signaling. HAPS Educato, 23(2), 420-25. https://doi.org/110.21692/haps.2019.017
- Shields, W. D. (2006). Infantile spasms: little seizures, BIG consequences. Epilepsy currents, 6(3), 63–9. https://pubmed.ncbi.nlm.nih.gov/16761063/
- Stahmer, A. C., Suhrheinrich, J., Schetter, P. L., & Hassrick, E. Mc. (2018). Exploring multi-level system factors facilitating educator training and implementation of evidence-based practices (EBP): A study protocol. Implementation Science, 13, 3. DOI: 10.1186/s13012-017-0698-1. https://implementationscience.biomedcentral.com/articles/10.1186/s13012-017-0698-1
- Wegiel, J., Kuchna, I., Nowicki, K., Imaki, H., Wegiel, J., Marchi, E., … & Wisniewski, T. (2010). The neuropathology of autism: Defects of neurogenesis and neuronal migration, and dysplastic changes. Acta Neuropathologica, 119(6), 755–770. https://doi.org/10.1007/s00401-010-0655-4
- Wilson, T. W., Rojas, D. C., Reite, M. L., Teale, P., & Rogers, S. J. (2007) Children and adolescents with autism exhibit reduced MEG steady-state gamma responses. Biological Psychiatry 62, 192–197. https://www.sciencedirect.com/science/article/abs/pii/S0006322306008663
- World Health Organization. (2024). ICD–11. International Classification of Disease 11ht Revision. World Health Organization. https://icd.who.int/es/