Abstract :

The Plants under study were extracted by different  solvents  with  increasing in polarity , petroleum ether, ethyl acetate and methanol extracts of some medicinal plants (Glinus lotodios (seeds), Eclipta alba (whole plant) and Ethulia conyzoides (Aerial parts) commonly used to treat a variety of ailments. And investigated for their antibacterial activity against four standard bacterial strains Bacillus subtilis (NCTC 8236), Staphylococcus aureus(ATCC 25923), Escherichia coli (ATCC 25922),  Pseudomonas aeruginosa (ATCC 27853), and two standard fungal strains Aspergilliu sniger (ATCC 9763) and Candida albicans (ATCC7596) in vitro. The plants extracts at a concentration of 100 mg/ml were applied using the agar plate well- diffusion method. the ethyl acetate and methanol extracts obtained from Ethulia conyzoides give more crude extract were showed high activity against all tested organisms, while the methanol extract of Glinus lotodios showed significant of all tested bacterial only and have no sensitivity towards fungal strains . The least antimicrobially active plant was Ethulia conyzoides. Ethulia conyzoides have more crude extract of methanol ( 9.81) and showed  broader spectrum towards Bacillus subtilis( I Z = 32mm) . The methanol extract of Ethulia conyzoidesis suitable candidates for the development of novel antibacterial compounds.

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Keywords :

medicinal plants – Ethulia conyzoides - methanol - antimicrobil - Bacillus subtilis×

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