Abstract :

Postoperative thromboembolic complications worldwide tend to increase in frequency, which is the cause of disability and mortality. The authors note that the risk of developing feasibility study can vary significantly depending on the nature of the operation, its duration, the type of anesthesia and the general somatic background of the patient. There are no existing schemes for the use of drugs for this disease, and methods for the prevention of feasibility studies are carried out without taking into account the state of the blood coagulation and anti–coagulation system. Patients suffering from obesity are most prone to EFT. Among obese individuals, calculous cholecystitis is more common than in people with normal body weight. Therefore, there is an urgent need for further study of the state of the blood coagulation and anticoagulation system in obese patients with ACC.

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Keywords :

acute calculous cholecystitis., Cholelithiasis, pulmonary embolism, thromboembolic complications

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References :

1. Avdeev S.N., Vavilova T.V., Goncharova N.S. 2019 European Guidelines for the Diagnosis and Treatment of Acute Pulmonary Embolism: Comments by Specialists of the Russian Cardiology and Respiratory Societies. Arterial hypertension. 2019; 25 (6):584–603.
2. Galperin E.I. Obstructive jaundice: the state of “imaginary stability”, the consequences of the “second blow”, the principles of treatment / Galperin E.I. // Annals of surgical hepatology. – 2011. – No. 16(3). – p. 16–
3. Dadvani S.A., Vetshov P.S., Shulutko A.M., Prudkov M.I. Gall stone disease. : ed. GEOTAR–Media group, 2009. – p. 175.
4. Zhukova E.V., Kunitsyna M.A., Kashkina E.I., Semikina T.M. Formation of an atypical clinical picture of chronic cholecystitis in patients with type 2 diabetes mellitus in the presence of autonomic diabetic neuropathy. Difficult patient. – – T.16. – No. 3. – p. 37–40.
5. Ivashkin V.T., Maev I.V., Baranskaya E.T. and other Recommendations of the Russian Gastroenterological Association for the diagnosis and treatment of cholelithiasis. // Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2016; 26(3):54–
6. Kartasheva A. Thromboembolism of the pulmonary artery. New ESC guidelines (2008) // Medicine Review . – V. 04. – T.4. – 56–64.
7. Konopleva L.F. Pulmonary embolism: diagnosis and treatment in the light of the recommendations of the Eurasian Society of Cardiology (2008). // Health. 2008. – p. 55–58.
8. Lebedev P.A., Dausheva A.Kh., Ayupov A.M. Pulmonary embolism in clinician practice: risk stratification, diagnostic and treatment algorithms. Samarkand. Honey. Univ. 2015. – p.
9. Mazaeva L.A. Pulmonary embolism (PE)., 2016. https://pateroclinic.ru/pulmonolo gia/tela.
10. Maistrenko H.A. Syndrome of obstructive jaundice of benign genesis: optimization of diagnostic and therapeutic approaches / H.A. Maistrenko, P.N. Romashchenko, E.Yu. Strukov // Actual problems of surgical hepatology: Proceedings of the XX International Congress of the Association of Surgeons–Hepatologists of the CIS countries. – Donetsk: Publisher Zaslavsky A.Yu., 2013. – p.
11. Mashrapov O.A., Abdurakhmanov A.A. Our experience of surgical treatment and prevention of transient pulmonary embolism. // XXIII Annual Session A.N. Bakulev. May 19–21, 2019.
12. Moiseeva O.M. Pulmonary embolism diagnostic and treatment algorithm. : GEOTAR–Media, 2016.
13. Musinov I.M. Homeostasis system Bulletin of the Russian Military Medical Academy. 3(55), 2016. – p. 167–170.
14. Nikitina O.V., Mikhailov I.P., Kudryashova N.E. Thrombolytic and anticoagulant therapy in pulmonary embolism with high and intermediate risk of early death. // Journal them. V. Sklifasovsky “Emergency medical care”. 2018; 7(3):209–216.
15. Panchenko E.P. Diagnosis and treatment of pulmonary embolism. Clinical recommendations of the Eurasian Association of Cardiology for practitioners (2021) // Eurasian Journal of Cardiology. (1) 2021. – p. 44–57.
16. Perepech N.B. Pulmonary embolism: diagnosis and treatment // Medical Council. No. 12. – p. 48–57.
17. Podlipaeva A.A., Mullova I.S., Pavlova T.V. New biological markers for diagnosing and predicting the risk of death in patients with pulmonary embolism. // Russian Journal of Cardiology. 2020; 25(4S):4202.
18. Podoplelova N.A., Sulimov V.B., Tashchilova A.S. Blood coagulation in the XXI century: new knowledge, methods and prospects for therapy. // Questions of hematology/oncology and immunopathology in pediatrics. 2020, 19(1):139–
19. Savelyev V.S., Chazov E.I., Gusev E.I. et al. Russian clinical guidelines for the diagnosis, treatment and prevention of venous thromboembolic complications // Phlebology. – 2010. – No.4. – p. 1–40.
20. Silina E.V., Rumyantseva S.A., Kabaeva E.N., Stupin V.A. Problems of the blood coagulation system and thromboembolic complications in the acute period of stroke // Almanac of Clinical Medicine. 2018. 44(3): 270–279.
21. Statkevich T.V., Pateyuk, I.V., Ilyina T.V., Demidovich D.V., Yanukovich A.S., Mitkovskaya N.P. Treatment of massive pulmonary embolism at the present stage. // Urgent cardiology and cardiovascular risks, 2017. Vol.1, No.1. – p. 46–51.
22. Shatalova O.V., Smuseva O.N., Maslakov A.S., Gorbatenko V.S. Thromboembolism of the pulmonary artery: diagnosis and treatment // Medicinal Bulletin. Volume 9, 4(60). – p. 42–54.
23. Daley M.J., Pharm D.B., Sadia Ali, et al. Late venous thromboembolism Profilaxir after Craniotomy in Acute Traumatic Brain ingury // The American surgeon. 2015. https://doi.org/10. 1177/000313481508100236.
24. De Gregorio MA, Guirola JA, et al. Interventional radiology treatment for pulmonary embolisim // World J. Radiol. 2017. ((7): 295–
25. Garcia D., Baglin T., Weitz J., et al. parenteral anticoagulants. Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence–Based Clinical Practice Guidelines // Chest. – 2012. – Vol. 141 (Sup. 2). – p. 24–43.
26. Kearon C, Ageno W, Cannegieter SC et al. Categorization of patients as having provoked or unprovoked venous thromboembolism: guidance from the SSC of ISTH. J Thromb Haemost. 2016, 14(7):1480–
27. Kirienko A., Chernyavskiy A.M., Andryashkina V.V. red. Tromboemboliyalegochnych artery. Kaklechit’ipredotvraschat [Thromboembolism of pulmonary arteries. How to treat and prevent]. M.: Medizinskoe informazionnoe agentstvo, 2015. – p. 275. (in Russian).
28. Konstantinides SV 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism. Eur Heart J, 2014, Vol. 53, No. 45. – 3145–3146.
29. Konstantinides S.V, Meyer G., Becattini C., et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC). European Heart Journal. 2020, 41(4):543–
30. Littlefield A., Lenahan C. Cholelithiasis: Presentation and Management // Journal of Midwifery & Women’s Health. – 2019. – Vol. 64. – No. 3. – p. 289–297.
31. Mahan C.E. Regulatory, policy and quality update for venous thromboembolism and stroke in United States hospitals. Thromb Res. 2012, 130(4):586–90. 10.1016/j. thromres.2012.07.001.
32. Meyer, G. Effective diagnosis and treatment of pulmonary embolism: Improving patient outcomes. Arch Cardiovascular Disease, 2014, Vol. 107, No. 6– – p. 406–414.
33. Monreal M., Mahe I., Bura–Riviere A., Prandoni P, Verhamme P, Brenner B., Wells P S., Di Micco P, Bertoletti L. Pulmonary embolism: Epidemiology and registries. Presse Med, 2015, Vol. 44, No. 12. – p. 377–383.
34. Meyer, G. Effective diagnosis and treatment of pulmonary embolism: Improving patient outcomes. Arch Cardiovascular Disease, 2014, Vol. 107, No. 6–7. – p. 406–414.
35. Pak M., Lindseth G. Risk Factors for Cholelithiasis // Gastroenterology Nursing: The Official Journal of the Society of Gastroenterology Nurses and Associates. – 2016. – Vol.39. – No.4. – p. 297–309.
36. Pyko A.A., Grigorenko E.A., Statkevich T.V. et al. Vnezapnaya serdechnaya smert’: epidemiologicheskie aspekty, vozmozhnosti profilakticheskich technologiy. Kardiologiya v Belarusi, 2016, No.4. – p. 534–553. (in Russian).
37. Righini M., Robert–Ebadi H., Le Gal G. Diagnosis of pulmonary embolism. Presse Med, 2015, Vol. 44, No.12. – p. 385–391.
38. Schulman S., Kakkar AK, Goldhaber SZ, et al. Treatment of acute venous thromboembolism with dabigatran or warfarin and pooled analysis // Circulation. – 2014. – Vol. 129 (7). – p. 764–772.
39. Turan O., Turgut D., Gunay T., Yilmaz E., Turan A., Akkoclu A. The contribution of clinical assessments to the diagnostic algorithm of pulmonary embolism. Adv Clin Exp Med, 2017, Vol. 26, No. 2. – p. 303–309.
40. Wendelboe A.M., Raskob G.E. Global burden of thrombosis: epidemiologic aspects. Circ Res. 2016; 118:1340–
41. World Health Organization. fact sheet No. 377. World Health Organization website 2017. http://www.who.int/mediacentre/factsheets/fs377/en/.