Abstract :
The article is devoted to the results of studies on the development of thin–layer chromatography (TLC) and UV–spectrophotometry analysis methods and introduction of ketamine to the determination of the substance extracted from the composition of biological fluids. The methods developed during the research were applied to the analysis of ketamine extracted from biological fluids and positive results were obtained.
Keywords :
extraction from biofluids (blood, ketamine, poisoning., thin layer chromatography, thin–layer chromatography (TLC), ultraviolet–spectrophotometry, urine)References :
- Yuldashev Z.A. Annals of Development Analysis Methods of Pesticides Acetomipride Isolated from a Biological Object by UV–Spectrophotometry / Z.A. Yuldashev, M.I. Nurmatova // of the Romanian Society for Cell Biology R.S.C.B., ISSN: 1583–6258, Vol. 25, Issue 2, 2021. – p. 4067–4073.
- Нурматова, М.И. Имидоклоприд ва ацетомиприд пестицидларини юпқа қатлам хроматографик таҳлил услубини ишлаб чикиш // М.И. Нурматова, З.А. Юлдашев / Фармацевтика журнали, Т. – №1. – c. 48–54.
- Клиническая анестезиология / Дж. Эдвард Морган. Мэгид С. Михаил, Майкл Дж. [ва бошқалар.] // Книга 1. – Бином, 2001. – 396 с.
- White, PF. Ketamine–its pharmacology and therapeutic uses / White PF, Way WL, Trevor AJ // (1982). Anesthesiology 56 (2): 119–36.
- Norman Calvey, N.E. Williams Principles and Practice of Pharmacology for Anaesthetists / Norman Calvey, N. E. – Wiley–Blackwell, 2001. – 357 с.
- Nurmatova M.I., Yuldashev Z.A. Development the method of thin–layer chromatographic analysis of imidocloprid and acetomiprid pesticides // Journal of Pharmacy. – – № 1. p. 48–54.
- Roslavtseva, S.A. Study of colorado beetle population / S.A. Roslavtseva, L.N. Didenko // Agrochemistry. – – № 4. – p. 80–85.
- Eremina, O.Yu. Synergistic effect of binary mixtures of neonicotinoids and pyrethroids on insects / O.Yu. Eremina, I.V. Ibragimkhalilova // Agrochemistry. – – № 2. – p. 37–44.
- Lopatina Yu.V. The use of neonicotinoids in the fight against ants / Yu.V. Lopatina, O.Yu. Eremina // Agrochemistry. – 2010, № 1. – 86–93.
- Khairullin D.D., Khalikova K.F., Yamalova G.R. and others. Pathomorphological and histological studies in case of poisoning of calves with synthetic pyrethroid against the background of the use of an antidote. N.E. Baumana. – №4, Tom. 228 – p. 16–18.
- Yuldashev Z.O., Bekchanov X.N., Shadmanova D.A. Development of conditions for the analysis of pesticide cypermethrin by thin–layer chromatography and UV spectrophotometry // Pharmaceutical journal. 2004. – № 4. – 40–42.
- Khayrullin D.D. Pathomorphological and histological studies in case of poisoning of calves with synthetic pyrethroid against the background of the use of an antidote / Khayrullin D.D., Egorov V.I., Khalikova K.F., Gubeeva E.G., Valiullin L.R. “Actual problems of scientific and personnel support for the innovative development of the agro–industrial complex” FSBEI “HPE Kazan State Academy of Veterinary Medicine named after N.E. Bauman”. Kazan, 2014. Volume 212. – 198–20.