Abstract :

Introduction: Exercise is regarded as an important adjuvant therapy for reducing the negative effects of Antiretroviral Therapy and improving the health status of people living with HIV (PLWH), but there is limited evidence on the effects of circuit exercise training on PLWH.
Objective: This study determined the effects of circuit exercise on the cardiorespiratory fitness and health status of PLWH.
Methods: This pretest-posttest randomized control study recruited 120 PLWH from the HIV clinic at Alex Ekwueme Federal University Teaching Hospital, Abakaliki. Participants were consecutively invited at the clinic to join the study. Fish bowl method was used to randomize the participants to either intervention group or control group. Moderate intensity (50 – 75% MHR) circuit exercise training was administered to the participants 3 times a week, between 30-60 minutes per session, for 8 weeks. Cardiorespiratory fitness and health status were measured at baseline and at 8-week. Descriptive statistics of mean, standard deviation, percentages, and bar chart was used to summarize data. Paired sample t-test and independent sample t-test were used to determine the mean difference within and between the groups respectively. Alpha level was set at P<0.05. Results: There was statistically significant difference in mean score of cardiorespiratory fitness and health status within the intervention group, and between the groups after 8-week circuit exercise training. Bar chart showed improvement in all the domains of health status.
Conclusion: An 8-week circuit exercise training improved cardiorespiratory fitness, and health status of PLWH.

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Keywords :

Aerobic capacity, Cardiorespiratory fitness, Circuit exercise, Health Status., HIV/AIDS

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References :

1. Gomes Neto, M., Conceição, C.S., Oliveira Carvalho, V., Brites, C. Effects of Combined Aerobic and Resistance Exercise on Exercise Capacity, Muscle Strength and Quality of Life in HIV-Infected Patients: A Systematic Review and Meta-Analysis. PLoS One, 2015; 10 (9): e0138066. doi:10.1371/journal.pone.0138066
2. Cade, W.T., Peralta, L., & Keyser, R.E. Aerobic exercise dysfunction in human immunodeficiency virus: a potential link to physical disability. Physical Therapy, 2004; 84:655-664.
3. Olgalha, C., Luz, E., Sampaio, E., Souza, R., Zarife, A., Neto, M.G., Brites, C. A randomized Clinical trial to evaluate the impact of regular physical activity on the Quality of life, body morphology and metabolic parameters of patients with AIDS. Journal of acquired immune deficiency syndromes, 2011; 57: s179-s185.
4. Keyser, R.E., Peralta, L., Cade, W.T., Miller S., & Anixt, J. Functional aerobic impairment inadolescents seropositive for HIV: A quasi experimental analysis. Archives of Physical Medicineand Rehabilitation, 2000; 81(11): 1479-1484.
5. MacArthur, R.D., Levine, S.D., Birk, T.J. Supervised exercise training improves cardiopulmonary fitness in HIV-infected persons. Medicine and Science in Sports and Exercise, 1993; 25(6): 684-688.
6. Lox, C.L., MaCuley, E., & Tucker, R.S. Aerobic and resistance exercise training effects on body composition, muscular strength and cardiovascular fitness in an HIV-1 population. International Journal of Behavioral Medicine, 1996; 3(1): 55-69.
7. Tiozzo, E. The Effect of Combined Moderate-Intensity Training on Immune Function, Metabolic Variables, and Quality of Life in HIV-infected Individuals Receiving Highly Active Antiretroviral Therapy. Open Access Dissertations, 2011; Paper 678.
8. American Thoracic Society. Quality of Life Resources: Health Status, Health Perceptions. 2007.
https://qol.thoracic.org/sections/key-concepts/health-status-health-perceptions.html
9. American College of Sports Medicine ACSM’s Guidelines for Exercise Testing and Prescription. 2010. 8th ed.Philadelphia.PA: Wolters Kluwer/Lippincott Williams & Wilkins.
10. Gomes Neto, M., Zwirtes, R., & Brites, C. A literature review on cardiovascular risk in human immunodeficiency virus-infected patients: implications for clinical management. Brazilian Journal of Infectious Diseases, 2013; 17(6): 691-700.
11. Terry, L., Sprinz, E., Stein, R., Medeiros, N. B., Oliveira, J., & Ribeiro, J. P. Exercise training in HIV-1-infected individuals with dyslipidemia and lipodystrophy. Medicine and Science in Sports and Exercise, 2006; 38, 411-417
12. Roubenoff, R., McDermott, A., & Weiss, L. Short-term progressive resistance training increases strength and lean body mass in adults infected with human immunodeficiency virus. AIDS, 1999; 13: 231-239.
13. Becker, S.L., Dezii, C.M., Burtcel, B., Kawabata, H., and Hodder, S. Young HIV-infected adults are at greater risk for medication nonadherence. General Medicine, 2002 4 (3): 21-25.
14. Tran BX, Ohinmaa A, Nguyen LT. Quality of life profile and psychometric properties of the EQ-5D-5L in HIV/AIDS patients. Health Qual Life Outcomes. 2012; 1;10:132. doi: 10.1186/1477-7525-10-132. PMID: 23116130; PMCID: PMC3541089
15. Tanaka H, Monahan KD, Seals DR. Age-predicted maximal heart rate revisited. Journal of American College of Cardiology, 2001; 37:153–156
16. O’Brien KK, Davis AM, Chan Carusone S, Avery L, Tang A, Solomon P, et al. Examining the impact of a community-based exercise intervention on cardiorespiratory fitness, cardiovascular health, strength, flexibility and physical activity among adults living with HIV: A three-phased intervention study. PLoS ONE, 2021; 16(9): e0257639. https://doi.org/10.1371/journal.pone.0257639
17. Ibeneme, S.C., Omeje, C., Myezwa, H., Ezeofor, S.N., Anieto, E.M., Irem, F., Nnamani, A.O., Ezenwankwo, F.E., Ibeneme, G.C. Effects of physical exercises on inflammatory biomarkers and cardiopulmonary function in patients living with HIV: a systematic review with meta-analysis. BMC Infectious Disease, 2019; 19: 359
18. John, D.O., Tella, B.A., Olawale, O.A., John, J.N., Adeyemo, T.A., and Okezue, O.C. Effects of a 6-week aerobic exercise programme on the cardiovascular parameters, body com-position, and quality of life of people living with human immune virus. Journal of Exercise Rehabilition, 2018; 14: 891-898.
19. Renuka, P., Apury, S., Savita, R., Ashok, S., & Parag, S. Effects of fitness training on physical fitness parameters and quality of life in human immunodeficiency virus-positive Indian females. Indian Journal of sexually transmited disease and AIDS, 2017; 38 (1): 47-53.
20. Johnson JE, Anders GT, Blanton HM, Hawkes CE, Bush BA, McAllister CK, Matthews JI. Exercise dysfunction in patients seropositive for the human immunodeficiency virus. American Review of Respiratory Disease, 1990; 141 (3):618-22. doi: 10.1164/ajrccm/141.3.618. PMID: 2310095
21. Blair SN, Cheng Y, Holder JS. Is physical activity or physical fitness more important in defining health benefits?. Medicine & Science in Sports & Exercise, 2001; 1;33(6):S379-99.
22. Shitu, A., Badirudeen, A., Abubakar, M.S., & Mohammed, J. Effect of aerobic exercise on functional capacity and health status of individuals living with HIV/AIDS in Kano, Nigeria: a randomized controlled pilot study. Nigerian Journal of Medical Rehabilitation, 2017; 19 (1): DOI:10.34058/njmr.v19i1.151
23. Perna, F.M..; laperriere, A., klimas, N.,Ironson, G., Perry, A., Pavone, J., Goldstein, A.,Majors, P., Makemson, D., Talutto, C., Schneiderman, N., Ann fletcher, M., Meijer, O.G., & Koppes, l. Cardiopulmonary and CD4 cell changes in response to exercise training in early symptomatic HIV infection. Medicine & Science in Sports & Exercise, 1999; 31 (7): 973-979.
24. Penedo, F.J., & Dahn, J.R. Exercise and well-being: a review of mental and physical health benefits associated with physical activity. Current Opinion in Psychiatry, 2005; 18 (2): 189-193.
25. Saxena, S., Van Ommeren, M., Tang, K.C., & Armstrong, T.P. Mental health benefits of physical activity. Journal of Mental Health, 2005; 14 (5): 445-451