Abstract :

Oral hygiene was associated with cardiovascular diseases (CVD), and the link is verified by bacterial colonization of the oral cavity and their products that spread into the circulation, starting endothelial dysfunction, pro-atherogenesis, pro-inflammation, and host immune mechanisms. High levels of serum uric acids are linked with CVD that are intern, associated with worsening gum hygiene. Several studies show that hyperuricemia could modify purine catabolism in case of oral disorders, including periodontal diseases (PD) and dental loss. PD and tooth caries were also linked with diabetes mellitus hypertension, insulin resistance, metabolic syndrome, dyslipidemia, and CVD. Dental caries was defined as an independent risk factor for coronary atherosclerosis too. However, dental restoration was correlated with the burden of arteriosclerosis negatively. Several experimental trials did not affirm the relationship between oral hygiene and CVDs.

Recent research has revealed similar biochemical and inflammatory biomarkers that are involved in CVD and oral diseases like C-reactive protein, interleukins, TNF-α, and others.

This consensus review aims to summarize some of the biochemical and inflammatory evidence connecting poor oral hygiene with the risk of CVD.

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Keywords :

ASCVD, Biomarkers, Cardiovascular diseases, Dental caries, Inflammation, Oral hygiene, Periodontal diseases., Periodontitis

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