Abstract :
In plant kingdom, medicinal plants are main important resource for a variety of drug like emetics, anti-cancer and antimicrobials. Medicinal herbs are highly cultured in India, which includes more than 2000 species are present. Grapes are soft fruit crop belongs to the Family of Vitaceae and Genus of Vitis. Grapes contain excellent source of nutritional values such as vitamins, minerals, proteins and carbohydrate. In this present work, various phytochemical constituents of grapes were identified in different extracts (Ethanol, Acetone and Aqueous). These phytochemicals are used for the treatment of several diseases. The antioxidant property of different extracts of grapes shows better result. The ellagic acid and the natural phenolic antioxidants were also identified. The antimicrobial activity of various grapes extract shows better result against Enterococcus and E.coli sps. Finally, the grape fruit is a wonderful antioxidant and antimicrobial agent.
Keywords :
Antibacterial, Antioxidants., Ellagic acid, phytochemicalsReferences :
1. Agustin ET (2007). Dayaantibakteriekstrakbuahmakutadewa (Phaleriamacrocarpa (Scheff) Boerl) terhadapbakteri Streptococcus alpha haemolyticus: penelitianlaboratoris. Bachelor Thesis.UniversitasAirlangga, Surabaya
2. Ali, Y. M., Iqbal, S. Z. A. Shah, and M. J. Ahmed. 2003. Effect of different combinations of nitrogen, phosphorous and farm yard manure on yield and quality of strawberry. Sarhad J. Agric. 19: 185-188
3. Ames,B.N.,M.K.Shigena, and T.M. Hagen.1993.Oxidants,antioxidants and the degenerative diseases of aging.Proc.natl.Acad.Sci.U.S.A.90;7915-7922
4. Anastasiadi M, Chorianopoulos NG, Nychas GJ, Haroutounian SA. Antilisterial activities of polyphenolrich extracts of grapes and vinification byproducts. J Agric Food Chem. 2009;57(2):457-63
5. Aravindaram K &Yang NS, 2010. “Anti-inflammatory plant natural products for cancer therapy”, Plantamedica, vol :76(11), pg : 1103-1117. Doi:10.1055/ s-0030-1249859
6. A.R. Törrönen, Identification and quantification of phenolic compounds in berries of Fragaria and Rubus species (Family Rosaceae), J. Agric. Food Chem. 52 (2004) 6178–6187
7. Bagchi D, Bagchi M, Stohssj, Das D k, Ray CA, et.al(2000) Free radicals and grape fruit proanthocyanidin extract; importance in human health and disease prevention J. Toxicol 148.187-197
8. 8] Brooks JT, Bergmire-Sweat D, Kennedy M, Hendricks K, Garcia M, Marengo L, Wells J, Ying M, Bibb W, Griffin PM, Hoekstra RM, Friedman CR (2004). Outbreak of Shiga toxin-producing Escherichia coli O111:H8 infections among attendees of a high school cheerleading camp. Clin Infect Dis 38, 190-198
9. D. Iveković, S. Milardović, M. Roboz, B. S. Grabarić, The Analyst 130 (2005) 708
10. F. A. Tomas-Barberan, M. N. Clifford, J. Sci. Food Agric. 80 (2000) 1024
11. Gupta SS. Prospects and Perspectives of Natural Plant Products In Medicine. Indian Journal of Pharmacol. 1994; 26:1-12
12. grosvenor et al 1995; ratnakar and murthy 1995; silva et al 1996; David 1997; saxena 1997; nimri et al 1999; saxena and sharma 1999).
13. Hausteen B. Flavonoids, a class of natural products of high pharmacological potency. Biochem Pharm. 1983; 32:1141-1148
14. Häkkinen, S.H. and A.R. Törrönen. 2000. Content of flavonols and selected phenolic acids in strawberries and Vaccinium species: Influence of cultivar, cultivation site and technique. Food Res. Intl. 33:517-524
15. Indian Horticulture Database. 2014. Ministry of Agriculture, Government of India, Gurgoan. Website: www.nhb.gov.in. 3307 Vijay Kumar, M. Pal, R.S. Singh, A.P. Singh, M.D. Ojha, R.K. Verma, R.B. Verma and P.K. Singh
16. Kammerer D, Claus A, Carle R and Schieber A. Phenolic screening of pomace from red and white grape varieties (Vitis vinifera L.) By HPLC-DAD-MS/ MS. J Agric Food Chem 2004; 52:4360-4367. 7. Rodriguez MR, Peces RR, Vozmediano CJL, Gascuena MJ and Romero GE. Phenolic compounds
17. Lee S, San D, Ryu J, Lee YS, Jung SH, Kang J. Antioxidant activities of Acanthopanaxsenticosus stems and their lignin components. Arch Pharm Res. 2004;27:10610
18. Li H, Wang Z, Liu Y. Review in the studies on tannins activity of cancer prevention and anticancer. Zhongyao-Cai. 2003; 26(6):444-448
19. Li H, Wang X Li P, Li Y, Wang H (2008) Comparative study of antioxidant activity of grape (Vitis vinifera) Assessed different method.J food drug analysis1-7
20. M. Kopjar, D. Šubarić, V. Pližota, Glukozinolati: Biodostupnost i utjecajnazdravljeljudi, J. Hum. Nutr.Diet. 1 (2012) 22–35. [2] K.R. Määttä-Riihinen, A. Kamal-Eldin
21. M. N. Clifford, A. Scalbert, J. Sci. Food Agric. 80 (2000) 1118
22. Ricardo da Silva JM. Monomeric, oligomeric, and polymeric flavan-3-ol composition of wines and grapes from Vitis vinifera L. Cv
23. singliton VL, Tannins and the qualities of wines ,in laks P.E. and Hemingway, R.W. (eds) Plant Polyphenols. Plenum Press, New York, NY; 1992.P.859–880.:6475–6481
24. Tsao R, Deng Z. Seperation procedures for naturally occurring antioxidant phytochemicals. Chromatogr B. 2004; 12:85-99
25. United States Department of Agriculture (nd). US Strawberry Industry. Available from
http://usda.mannlib.cornell.edu/mannusda/viewdocumentinfo.do Documentid=1381. Accessed Juni 3, 2011
26. vennila S ,bupeshg,mathiyazhagank, baskerm, Amutha S ,et al. (2012) Qualitative photochemical Screening and In vitro antioxidant activity of Hisora,advanced biotech journal 14:3-20
27. Y. Amakura, M. Okada, S. Tsuji, Y. Tonogai, J. Chromatogr. A 896 (2000) 87
28. Serra AT,Matias A, nunesVM,LeitaoMC,Brito D, et.alinVitro Evaluation of Olive and Grape-Based Natural Extracts as Potential Preservatives for Food. Innovative Food Science And emerging technologies9(3):311-319