Abstract :
The leiomyosarcoma is a tumor of mesenchymal origin of smooth, malignant, slow-growing muscles. The present study reports a case of duodenal leiomyosarcoma in Labrador dog. A 6 year old black female Labrador dog with history off feed, vomition and melena brought for necropsy examination. Gross lesions revealed tennis ball size tumorus mass at the initial portion of duodenum resulting into the obstruction of intestinal lumen. Microscopically, duodenum with tumours mass revealed smooth muscle bundles arranged in all the directions having elongated blunt ended nuclei along with numerous blood vessels and mitotic figure which is indicative of leiomyosarcoma.
Keywords :
Labrador, Leiomyosarcoma, pathologyReferences :
- Swann, H.M. and Holt, D.E. Canine gastric adenocarcinoma and leiomyosarcoma: A retrospective study of 21 cases (1986-1999) and literature review. Journal of American Animal Hospital Association, 38:157-164, 2002.
- Leibman, N.F., Larson, V.S. and Ogilvie, G.K. Oncology diseases gastrointestinal tract. In: Tams, T.R., Ed., Handbook of small animal gastroenterology, 2nd Edition, Saunders/Elsevier, St. Louis, 385-392, 2005.
- Araujo, D. A., Santos, I.O.V., Silva, M.A., Pessoa, C.C.V., Carvalho, J.R.G., Lopes, N.L. and Fernandes, J.I. Sarcoma Gastrointestinal. Revista Brasileira de Medicina Veterinária, 38:178-182, 2016.
- Frgelecová, L., Škoric, M., Fictum, P. and Husník, R. Canine gastrointestinal tract tumours: A retrospective study of 74 Cases. Journal Acta Veterinaria Brno, 82: 387-392, 2013
- Luna, L.G. Manual of histologic staining methods of the Armed Forces Institute of Pathology, 3rd Ed. McGraw Hill Book Co., London: 124 – 125, 1968
- Cohen, M., Post, G.S. and Wright, J.C. Gastrointestinal leiomyosarcoma in 14 Dogs. Journal of Veterinary Internal Medicine, 17:107-110, 2003
- Calesso, J., Mariah, C., Thalita E.,Izabelle, G. C., Michelle C.S., Giovana D., Carmen L., Patrícia M. and Mauro, C. Gastric leiomyosarcoma associated with hypoglycemia in dog—A case report. Open Journal of Veterinary Medicine, 9:12-18, 2019
- Frost, D., Lasota, J. and Miettinen, M. Gastrointestinal stromal tumors and leiomyomas in the Dog: A histopathologic, immunohistochemical and molecular genetic study of 50 cases. Veterinary Pathology, 40: 42-54, 2003.